B2ZXD5
Gene name |
GPR89 (GPHR) |
Protein name |
Golgi pH regulator |
Names |
Protein GPR89 |
Species |
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) |
KEGG Pathway |
cge:100689387 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B2ZXD5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B2ZXD5-F1 | Predicted | AlphaFoldDB |
No variants for B2ZXD5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B2ZXD5 | |||||
No associated diseases with B2ZXD5
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi cisterna membrane | The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| voltage-gated anion channel activity | Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| intracellular pH reduction | Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion. |
| protein transport | The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| regulation of ion transmembrane transport | Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. |
| T cell differentiation | The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFLIDSSIM | VTSQILFFGF | GWLFFMRQLF | KDYEVRQYVV | QVIFSVTFAF | SCTMFELIIF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EILGVLNSSS | RYFHWKMNLC | VILLILVFMV | PFYIGYFIVS | NIQLLHKQRL | LFSCLLWLTF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MYFFWKLGDP | FPILSPKHGI | LSIEQLISRV | GVIGVTLMAL | LSGFGAVNCP | YTYMSYFLRN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VTDTDILALE | RRLLQTMDMI | ISKKKRMAVA | RRTMFQRGEV | QNKPSGLWGM | LKSVTASAPG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SENLTLIQQE | VDALEELSRQ | LFLETADLYA | TKERIEYSKT | FKGKYFNFLG | YFFSIYCVWK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IFMATINIVL | DRVGKTDPVT | RGIEITVNYL | GIQFDVKFWS | QHISFILVGI | IIVSSIRGLL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| ITLTKFFYAI | SSSKSSNVIV | LLLAQIMGMY | FVSSVLLIRM | SMPPEYRTII | TQVLGELQFN |
| 430 | 440 | 450 | |||
| FYHRWFDVIF | LVSALSSILF | LYLAHKQAPE | KHMAP |