Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for B2W8X8

Entry ID Method Resolution Chain Position Source
AF-B2W8X8-F1 Predicted AlphaFoldDB

No variants for B2W8X8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B2W8X8

No associated diseases with B2W8X8

3 regional properties for B2W8X8

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 37 - 267 IPR003439
domain AAA+ ATPase domain 61 - 243 IPR003593
conserved_site ABC transporter-like, conserved site 168 - 182 IPR017871

Functions

Description
EC Number
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

1 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPKEHKKRGR REDQKKRKRD HDDESASKRF RKDDIEHVQA ENPLQHVAND APRQDAAPFY
70 80 90 100 110 120
GMLDEQEQEY FKKADEMLEL NQFESPEDRR IFLASVWKEA EGKELKMATS QTSRLLERLI
130 140 150 160 170 180
LLASEDQLKS LFQKFSGHFL NLVQNRFASH CCETLFIQAA PAVSQENASV KTEALNTPPA
190 200 210 220 230 240
SDPDEIIVSM ENLFLYTLGE LEGNIGFLMT EKYASHVLRV LLVILSGEPL EKQGKSVTQS
250 260 270 280 290 300
KKKEKVTISG AGDERILEKR VVPESFLEAL EKVISDSVSG IEAHYLRSLA IHPLGGPTLQ
310 320 330 340 350 360
LLLKLELSHF GKSRAKDEKS IIHRLLPDNP IAEGTESAIL INGLVYDSVG SHLLETIIEH
370 380 390 400 410 420
APGKLFKQIY GEFFKERMGS LARNEIAGYV VGKILERLGK DDLEEAMRQI VDQIPSLVER
430 440 450 460 470 480
NRTAPIKTLI ERCVAREVDC SPIKAQLETA YAGPHGFEVT RILKLNEDDG KPRARHGESN
490 500 510 520 530 540
EKVHGSLLAQ TMMTVDGPLG QLVFDSLANL SPELSIQLAR DGTASRTLQA ALVSRNATVI
550 560 570 580 590 600
FRRKMIQQFY GKIGELALDP KASHVVDAIW YGTVGLAFIR ERIAEELAEN ENSLRESQVG
610 620 630 640 650 660
RKVWKNWQMD LYKRRRNDWV AQARTTAGNE VFQSFPDESQ SDVAAPARTH RASRHMSAIE
670 680 690
LARQKFAAAK AAQAKDGKKP KKGNNPTNGS GETPRSLVAQ