B2W340

PR
Gene name
kex1 (PTRG_03838)
Protein name
Pheromone-processing carboxypeptidase kex1
Names
Carboxypeptidase D
Species
Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus) (Drechslera tritici-repentis)
KEGG Pathway
EC number
3.4.16.6: Serine-type carboxypeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

453-639 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B2W340

Entry ID Method Resolution Chain Position Source
AF-B2W340-F1 Predicted AlphaFoldDB

No variants for B2W340

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B2W340

No associated diseases with B2W340

2 regional properties for B2W340

Type Name Position InterPro Accession
domain Kinesin motor domain 260 - 598 IPR001752
conserved_site Kinesin motor domain, conserved site 490 - 501 IPR019821

Functions

Description
EC Number 3.4.16.6 Serine-type carboxypeptidases
Subcellular Localization
  • Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
serine-type carboxypeptidase activity Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

2 GO annotations of biological process

Name Definition
apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAFSHAPSGW RTALLAGLIA TVAWLPAIVA QEKTQADYFI HDLPGAPKPL LKMHAGHIEV
70 80 90 100 110 120
DAEHNGNLFF WHYQNRHIAD RQRTVLWLNG GPGCSSMDGA MMEIGPYRVR EGGKLEYNNG
130 140 150 160 170 180
SWDEFANLLF VDQPVGTGFS YVNTDSYLTE LDQMAAHMVI FLEKWFALFP EYENDDLYIA
190 200 210 220 230 240
GESYAGQHIP YIARAILDRN KKNQAKSPWP LKGLLIGNGW MSPVDQYLSY IPFAYQNGLM
250 260 270 280 290 300
RSGTDMAKRV EEQQRICVQK LEAGGMDAVD TRDCEQIMVR ILQETKNENA DPMNQCLNMY
310 320 330 340 350 360
DIRLRDDSSC GMNWPPDLAQ VTPYLRRADV VQALHINTDK KTGWQECNGA VSSHFRAKNS
370 380 390 400 410 420
KPSVKFLPEV IEQVPVLLFS GDKDFICNHV GTEAMIQNLQ WNGGKGFEAS PGVQNAKQDW
430 440 450 460 470 480
MFEGEAAGTW QEARNLTYVV FYNSSHMVPF DYPRRTRDML DRFMGVNIEA IGGAPADSLI
490 500 510 520 530 540
DGEKGPLTSV GDHPNSTKAE EDKSKELKAA EWKAYTRSGE VALVIAVIVA CICGFLLCRS
550 560 570 580 590 600
RRAKSAYKGD DSDEGRESLL TGMGLDNFRR KERRQDVEAA DFDERELDEV PKKSGKGYGQ
610 620 630
ISSEKGRVPH NDSSFSLGVD SDDDEAGSSD RGRRKEESR