B2VR76
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B2VR76
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B2VR76-F1 | Predicted | AlphaFoldDB |
No variants for B2VR76
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B2VR76 | |||||
No associated diseases with B2VR76
6 regional properties for B2VR76
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 422 - 470 | IPR001680-1 |
| repeat | WD40 repeat | 643 - 682 | IPR001680-2 |
| repeat | WD40 repeat | 686 - 726 | IPR001680-3 |
| repeat | WD40 repeat | 738 - 781 | IPR001680-4 |
| domain | BOP1, N-terminal domain | 163 - 422 | IPR012953 |
| conserved_site | WD40 repeat, conserved site | 448 - 462 | IPR019775 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| PeBoW complex | A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively. |
| preribosome, large subunit precursor | A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| large ribosomal subunit rRNA binding | Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA. |
| ribonucleoprotein complex binding | Binding to a complex of RNA and protein. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. |
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVNPRKRKV | VTRPAPEPSD | SEGELGDGLL | EGILSHSEDD | SDNSREEEVD | TDASSVIEGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SDEDEEEDED | SDSEQIRTEM | RNLNTSDGPL | RKKKGVPTHD | MDLDTAVTEE | LEDDEDLKPN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YTVTTDAHGN | TRYIYKEIDP | VYESDDSDVE | ATNTIGNIDL | KYYDEYPHIG | YDINGKKIMR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PAKGEALDAL | LDSIDIPKGW | TGLTDPQTGK | PLNLSEEELD | VLKRLTRNEV | VEDGYDPYPE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MVAYFSGKQE | IMPLSAAPEP | KRRFIPSKHE | AKRVMKLVKA | IREGRIQPYR | APEEQEEEQD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AFNFDVWADE | KPRPDNSMHI | PAPKLPPPGY | EASYHPPPEY | LPDKAEEQAW | LEADEEDRER |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EFLPKNYDAL | RKVPGYETFV | KERFERSLDL | YLAPRIRRNR | LNIDPESLLP | KLPNPEDLKP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| FPTTCAAIFR | GQEGRVRCVS | IDPNGIFVAS | GGDDGYVRIW | ELLTGRQVWN | AKLSDEEAVD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AVQWRPKKDA | SVVAAACGEN | VFLIVPFTLL | SPDVEQASRE | VLDAGWGYAT | SKPSTSSNGE |
| 550 | 560 | 570 | 580 | 590 | 600 |
| APKQAPGKWS | RPGARLENKG | VLVQVEVRSA | VKIVNWHRRG | DYFATVSPRG | QSTAVAIHTV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SKHLTQLPFR | RLKGIAQTAQ | FHPSKAIFFV | ATRNTIRSYD | LAKQELVKIL | QPGAKWISSI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| DVHPGGDNLI | VGTYDKRLLW | HDLDLSNKPY | KTLRFHKEAI | RAVRFHQGGL | PLFADTSDDG |
| 730 | 740 | 750 | 760 | 770 | 780 |
| TIQIFHGKVV | GDLMENATIV | PLKVLKGHKV | RSRLGVMGLD | WHPKEPWCVS | AGADGTLRLW |
| S |