Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for B2VC92

Entry ID Method Resolution Chain Position Source
AF-B2VC92-F1 Predicted AlphaFoldDB

No variants for B2VC92

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B2VC92

No associated diseases with B2VC92

2 regional properties for B2VC92

Type Name Position InterPro Accession
domain Nicotinate phosphoribosyltransferase, N-terminal domain 13 - 130 IPR040727
domain Nicotinate/nicotinamide phosphoribosyltransferase 169 - 395 IPR041525

Functions

Description
EC Number 6.3.4.21 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
nicotinate phosphoribosyltransferase activity Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate.

1 GO annotations of biological process

Name Definition
NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTRHAAPILT TLLDTDAYKL HMQQAVFHRY YDVTVTAEFR CRGEDMLGIY ADELVQQIAN
70 80 90 100 110 120
MASLTLTDNE FAYLSSLPFF KTDYLNWLRT FRYNPEQVTV QNLQGKLDIR ISGPWREVIL
130 140 150 160 170 180
WEVPLLALIS EVVHRHRSPQ ITPEQAVSRL KSKLEQFKRL TCDLDMSRFR LMDFGTRRRF
190 200 210 220 230 240
SHDVQLAVVS TLKQDFPWLV GSSNYDIARR LNIAPVGTQA HEWFQAHQQI SPTLENCQRA
250 260 270 280 290 300
ALQAWLDEYP DRLGIALTDC ITTDAFLRDF GSEFAHAYQG LRHDSGDPFE WGEKAIAHYQ
310 320 330 340 350 360
QLNIDPLSKT LVFSDNLDLD KAVGLYRHFE QRINVIFGIG TRLSCDIPQV KPLNIVIKLV
370 380 390 400
ECNGKPVAKL SDSPGKTICH DKAFVRALRK AFDLPRVKKA S