B2V7X0
Gene name |
tmk |
Protein name |
Thymidylate kinase |
Names |
dTMP kinase |
Species |
Sulfurihydrogenibium sp (strain YO3AOP1) |
KEGG Pathway |
sul:SYO3AOP1_0400 |
EC number |
2.7.4.9: Phosphotransferases with a phosphate group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B2V7X0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B2V7X0-F1 | Predicted | AlphaFoldDB |
No variants for B2V7X0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B2V7X0 | |||||
No associated diseases with B2V7X0
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.4.9 | Phosphotransferases with a phosphate group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| thymidylate kinase activity | Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| dTDP biosynthetic process | The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate). |
| dTTP biosynthetic process | The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGFFITFEGI | EASGKTTQIN | LLYDYLKSIG | KNVIKTREPG | GTKIGQKIRE | ILLSKWDEKF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PYIAELLLYE | SDRNIHIQSI | VKPSLDAGYI | VLSDRYIDST | TAYQHYARGI | DYEIVSYLNT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LATDGLKPNL | TFLIDIPVEI | SLKRLSESKD | RIESEDIEFH | KKLREGFLKI | AENEKGRFVV |
| 190 | 200 | ||||
| IDGTMDIMEI | HKIIVDSLKQ | RSII |