B2URE3
Gene name |
argB |
Protein name |
Acetylglutamate kinase |
Names |
N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK |
Species |
Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc) |
KEGG Pathway |
amu:Amuc_1203 |
EC number |
2.7.2.8: Phosphotransferases with a carboxy group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B2URE3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B2URE3-F1 | Predicted | AlphaFoldDB |
No variants for B2URE3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B2URE3 | |||||
No associated diseases with B2URE3
1 regional properties for B2URE3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aspartate/glutamate/uridylate kinase | 28 - 270 | IPR001048 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.2.8 | Phosphotransferases with a carboxy group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| acetylglutamate kinase activity | Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate. |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| arginine biosynthetic process via ornithine | The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDSKITRLIE | QASVIVGALP | YLQAYRDKTF | LIKFGGSAMD | DARLVKKLMR | DIVLLEVLGF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NPVIVHGGGK | AISKAMAEAG | LEARFVNGLR | VTTPEAISIV | ERTLSGTINP | GLVQMFRDYG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GKGVGIPGTE | IFVGERIHEK | DEQGNPIDIG | EVGNVIGCLT | ERITEALELQ | ITPIVSPLAK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ELGTHKPLNV | NADLAAAALA | KELKPVKLIY | ISDVPGIMKD | PSDPSTLIKS | VTRTEALDLI |
| 250 | 260 | 270 | 280 | 290 | |
| KDGTVSGGMI | PKIHSAIDAL | NAGVRKVHFI | DGRLPHTLLL | EIFTPDGIGT | EIIREQR |