B2UMV5
Gene name |
der |
Protein name |
GTPase Der |
Names |
GTP-binding protein EngA |
Species |
Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc) |
KEGG Pathway |
amu:Amuc_0319 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B2UMV5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B2UMV5-F1 | Predicted | AlphaFoldDB |
No variants for B2UMV5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B2UMV5 | |||||
No associated diseases with B2UMV5
7 regional properties for B2UMV5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 6 - 157 | IPR005225-1 |
| domain | Small GTP-binding protein domain | 190 - 360 | IPR005225-2 |
| domain | GTP binding domain | 7 - 122 | IPR006073-1 |
| domain | GTP binding domain | 191 - 309 | IPR006073-2 |
| domain | EngA-type guanine nucleotide-binding (G) domain | 5 - 169 | IPR031166-1 |
| domain | EngA-type guanine nucleotide-binding (G) domain | 190 - 368 | IPR031166-2 |
| domain | GTPase Der, C-terminal KH-domain-like | 372 - 458 | IPR032859 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| ribosome biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQHVPTIAIV | GRPNVGKSAI | FNRMAGRRIA | IVHDEPGVTR | DRLSAPCKIT | DRACKIMDTG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GIGARLSDGF | AEQVEAEADI | AIKTADLILF | VLDCRDHLTP | IDQSIADHLR | KSDIPVILLL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NKADHEKQDL | NLGEFAGLGF | DDHIFLSAAH | GRGFSELASR | LDGFLKQKGA | PLKEELEEEP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ENGEETALPI | KVAVVGRPNA | GKSSLVNAIL | RDRRTIVSNV | AGTTRDAIDV | PYLHDGQPYV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LIDTAGMRPR | SRRDTSVEVF | SAMRSEKAIR | RADICLLVID | IAAGITQQDR | RIAGIIAEEG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KPCIIIVNKF | DLFHPNASRK | DRMAEVEEQV | RRELFFISYA | PFIATSAKKA | EGVEIIFKVI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TRIRRESHNL | PTTGQLNRLI | QLAQQMNPPG | AASGSARRLK | IYYATTAVDP | KYNTIPVPRY |
| 430 | 440 | 450 | 460 | ||
| VLFVNDKSLL | TDSYSQYLRN | KIREAYPAPG | IPVIFSARSR | VRND |