B2UL12
Gene name |
glaA (Amuc_1463) |
Protein name |
Alpha-1,3-galactosidase A |
Names |
Exo-alpha-galactosidase A |
Species |
Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc) |
KEGG Pathway |
amu:Amuc_1463 |
EC number |
3.2.1.22: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B2UL12
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B2UL12-F1 | Predicted | AlphaFoldDB |
No variants for B2UL12
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B2UL12 | |||||
No associated diseases with B2UL12
1 regional properties for B2UL12
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Right handed beta helix domain | 461 - 580 | IPR039448 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.22 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| raffinose alpha-galactosidase activity | Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| metabolic process | The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQNPVASLLF | ILAMLTGPCP | AADYPERTER | TQSAGNHVWH | IDPDKGNDGN | PGTAPSTAWK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SMAPANRLIM | ARGDTLVIHP | GEHAVSLALM | GEGSKQAPVT | IRFMPGRHIF | KHGALMTGKP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QISNTNDAPN | EPKAMAIRLM | EAKNIRLEGK | PGATDILLEG | KAIFVCMEHA | ENVSLNGLGF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DYLHPTMGEF | LVTEVEGDTM | KATIPDGTLY | TVKDGNLTWH | GPGWEFRMGG | YSKVFDSASG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TFQGRFDPGK | TVIRELSPGK | ISITFKEGSP | TMKPGQSYQN | RNTRRDCCGF | FQYRSKNILW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NNCHIYYMHG | MGVVSQFCEN | IMFSHLKIAP | RPRSLRTNSS | WADNLHFSGC | RGKIIVKDCV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LGASHDDAVN | VHGTHLRIID | RPAPNKITVR | FMHPQTFGFD | AFAAGDRIDY | VSCNTLVPYA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SNTVSGVKQL | NEKEIELTLQ | HPNPGNIQPD | DVVENVTWTP | SVHISNTVCR | HIPTRGFLLT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TRKPVLVERC | RFEKTGMPAI | LVEDDASGWY | ESGVVRNMTI | SRNTFIQCGE | AVIQIVPHAP |
| 550 | 560 | 570 | 580 | 590 | |
| RPEGDVHRNI | TITGNTFDLK | NGTAIRIRHT | GDVKAEKNTF | TKDGKKIPEE | KAVDIR |