Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B2KIE9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B2KIE9-F1 | Predicted | AlphaFoldDB |
No variants for B2KIE9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B2KIE9 | |||||
No associated diseases with B2KIE9
1 regional properties for B2KIE9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Septin-type guanine nucleotide-binding (G) domain | 41 - 309 | IPR030379 |
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| anchoring junction | A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. |
| axon | The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. |
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
| presynapse | The part of a synapse that is part of the presynaptic cell. |
| synaptic vesicle membrane | The lipid bilayer surrounding a synaptic vesicle. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of intracellular protein transport | Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. |
| regulation of protein stability | Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation. |
| regulation of SNARE complex assembly | Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAATDLERFS | NAEPEPRSLS | LGGHVGFDSL | PDQLVSKSVT | QGFSFNILCV | GETGIGKSTL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MNTLFNTTFE | TEEASHHEEC | VRLRPQTYDL | QESNVQLKLT | IVDAVGFGDQ | INKDESYRPI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VDYIDAQFES | YLQEELKIRR | SLFDYHDTRV | HVCLYFITPT | GHSLKSLDLV | TMKKLDSKVN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IIPIIAKADT | ISKSELHKFK | IKIMGELVSN | GVQIYQFPTD | DEAVAEINAV | MNAHLPFAVV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GSTEEVKVGN | KLVRARQYPW | GVVQVENENH | CDFVKLREML | IRVNMEDLRE | QTHSRHYELY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RRCKLEEMGF | QDSDGDSQPF | SLQETYEAKR | KEFLSELQRK | EEEMRQMFVN | KVKETELELK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EKERELHEKF | EHLKRVHQEE | KRKVEEKRRE | LEEETNAFNR | RKAAVEALQS | QALHATLQQP |
| LRKDKDKKK |