B2K8U4

PR
Gene name
betA
Protein name
Oxygen-dependent choline dehydrogenase
Names
CDH, CHD, Betaine aldehyde dehydrogenase, BADH
Species
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
KEGG Pathway
ypb:YPTS_1275
EC number
1.1.99.1: With other acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

513-567 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B2K8U4

Entry ID Method Resolution Chain Position Source
AF-B2K8U4-F1 Predicted AlphaFoldDB

No variants for B2K8U4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B2K8U4

No associated diseases with B2K8U4

2 regional properties for B2K8U4

Type Name Position InterPro Accession
domain Glucose-methanol-choline oxidoreductase, N-terminal 3 - 300 IPR000172
domain Glucose-methanol-choline oxidoreductase, C-terminal 393 - 527 IPR007867

Functions

Description
EC Number 1.1.99.1 With other acceptors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
betaine-aldehyde dehydrogenase activity Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.
choline dehydrogenase activity Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde.
flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.

1 GO annotations of biological process

Name Definition
glycine betaine biosynthetic process from choline The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEYDYIIIGA GSAGNVLAAR LTEDADVTVL LLEAGGPDYR LDFRTQMPAA LAFPLQGKRY
70 80 90 100 110 120
NWAYETDPEP HMNNRRMECG RGKGLGGSSL INGMCYIRGN AMDFDHWASL SGLEDWSYLD
130 140 150 160 170 180
CLPYFRKAET RDVGPNDFHG GEGPVSVTTP KIDNNPLFHA MVAAGVQAGY PRTDDLNGYQ
190 200 210 220 230 240
QEGFGPMDRT VTPKGRRAST ARGYLDQARP RNNLTIITHA LTDRILFEGK RATGVSYLKG
250 260 270 280 290 300
DAGTGQTAHA RREVLLCGGA IASPQILQRS GIGPAELLQR LDIPLVQALP GVGENLQDHL
310 320 330 340 350 360
EMYLQYSCKQ PVSLYPALLW FNQPKIGIEW LFNGTGVGAS NQFEAGGFIR SRDAFTWPNI
370 380 390 400 410 420
QYHFLPVAIN YNGSNAVKEH GFQAHVGSMR SPSRGRIQVK SKDPRQHPSI LFNYMSNEQD
430 440 450 460 470 480
WHEFRDAIRI TREIIAQPAL DPYRGREISP GANVQSDDEL DAFIREHAET AYHPSCSCKM
490 500 510 520 530 540
GDDKMAVVDG QGRVHGVQGL RVVDASIMPQ IITGNLNATT IMIAEKIADR IRGCQPLAKS
550 560
NAAYFIAGDT PARTSPVRHS LPVTSYP