B2K103

PR
Gene name
coaA
Protein name
Pantothenate kinase
Names
Pantothenic acid kinase
Species
Yersinia pseudotuberculosis serotype IB (strain PB1/+)
KEGG Pathway
ypb:YPTS_0292
EC number
2.7.1.33: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-40 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B2K103

Entry ID Method Resolution Chain Position Source
AF-B2K103-F1 Predicted AlphaFoldDB

No variants for B2K103

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B2K103

No associated diseases with B2K103

3 regional properties for B2K103

Type Name Position InterPro Accession
domain Calcineurin-like phosphoesterase domain, ApaH type 106 - 306 IPR004843
domain Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase 78 - 369 IPR006186
domain PP2B, metallophosphatase domain 63 - 367 IPR041751

Functions

Description
EC Number 2.7.1.33 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
pantothenate kinase activity Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.

2 GO annotations of biological process

Name Definition
coenzyme A biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTKREQSLAT PYLQFDRTQW AALRDSVPLT LTEEEIVKLK GINEDLSLDE VAQIYLPLSR
70 80 90 100 110 120
LLNFYISSNL RRQAVLEQFL GTDGQRIPYV IGIAGSVAVG KSTTARLLQA LLSRWPEHRS
130 140 150 160 170 180
VELITTDGFL HPNKVLNERG LMKKKGFPES YDMHNLVKFV SEVKSGADYV TAPVYSHLIY
190 200 210 220 230 240
DVVPDGNKVI KQPDILILEG LNVLQSGMDY PHDPHHVFVS DFVDFSIYVD APEDLLQSWY
250 260 270 280 290 300
INRFLKFRQG AFSNPDSYFH NYAKLPETEA IKIATQLWNE INGLNLKQNI LPTRERASLI
310
MTKSANHAVE SVRLRK