B2JZ70
Gene name |
mutH |
Protein name |
DNA mismatch repair protein MutH |
Names |
Methyl-directed mismatch repair protein |
Species |
Yersinia pseudotuberculosis serotype IB (strain PB1/+) |
KEGG Pathway |
ypb:YPTS_3159 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B2JZ70
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B2JZ70-F1 | Predicted | AlphaFoldDB |
No variants for B2JZ70
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B2JZ70 | |||||
No associated diseases with B2JZ70
1 regional properties for B2JZ70
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DNA mismatch repair MutH/Type II restriction enzyme Sau3AI | 19 - 225 | IPR011337 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| endonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA modification | The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. |
| mismatch repair | A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVYSLPPAP | PSDEHQLFQR | AQALSGFTLG | ELATRAQWVI | PADLKRVKGW | VGMLLEFYLG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ASAGSKPEQD | FADIGIELKT | IPISAQGKPL | ETTFVCVAPL | TGNSGVTWEN | SHVRHKLARV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LWVPVEGERH | IPLAERRVGA | PLLWSPNVEE | EELLRRDWEE | LMDLIVLGKV | ESITARHGQV |
| 190 | 200 | 210 | 220 | ||
| LQLRPKAANS | RALTEAIGEF | GQPIMTLPRG | FYLKKTLTAP | MLARHFLL |