B2HX50

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Acinetobacter baumannii (strain ACICU)
KEGG Pathway
abc:ACICU_01240
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

780-865 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B2HX50

Entry ID Method Resolution Chain Position Source
AF-B2HX50-F1 Predicted AlphaFoldDB

No variants for B2HX50

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B2HX50

No associated diseases with B2HX50

5 regional properties for B2HX50

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 634 - 822 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 7 - 119 IPR007695
domain DNA mismatch repair protein MutS, core 292 - 615 IPR007696
domain DNA mismatch repair protein MutS, connector domain 127 - 262 IPR007860
domain DNA mismatch repair protein MutS, clamp 452 - 543 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNSAEIMADL SNHTPMMQQY LKVKKDYQHA LLFYRMGDFY ELFFEDAHLA AKLLGITLTH
70 80 90 100 110 120
RGKANGNPIP MAGVPYHSAE GYLARLVKAG RTVAICEQVG EVTGKGPVER KVVRILTPGT
130 140 150 160 170 180
LTDDALLTSY QSSNLVALCI HQNQIGFALL DLSAGIFKVQ QQDYKPEQLP IELARLMPSE
190 200 210 220 230 240
ILIDEDLVDP NIIEQIKKHL DCPVTKRPNV DFNLNNAQKT LCDQFSVSTL SGFGLDPLPL
250 260 270 280 290 300
AKAAAAALIH YAKETQKTAL PHIRSILLEQ SSDFIALDPI TRRNLEIIEP LFEHGTSLFQ
310 320 330 340 350 360
LVNDCQTAMG GRLLSRTLMQ PVRDTALLDA RLDAIEQLIQ GYHESPVRLV LKEIGDIERV
370 380 390 400 410 420
LSRVALGSAR PRDLVQLRHA CAQIPFLRNA LAPVVQAKKS KLLGQLDQEL GDFKSLHQHL
430 440 450 460 470 480
MAAIVENPPV LLRDGNVIAE GYDAELDELR QIRDHAGQFL IDLEIKERER TGISTLKIGY
490 500 510 520 530 540
NRVSGYYIEL TRAQAEQAPA DYIRRQTLKN AERYITPELK SFEDKVLSSE SRALAREKAL
550 560 570 580 590 600
FEALLENLRE NIAHLQMMSS AIAQIDVIAN FAHQARLNNW ARPEFTPETG IKIQGGRHPV
610 620 630 640 650 660
VEALSKAPFT PNDTFLDVQH RMAIITGPNM GGKSTFMRQT ALISLLAYCG SYVPARAAKL
670 680 690 700 710 720
GPIDRIFTRI GSADDLSTGK STFMVEMTET SQILHHATNQ SLVLMDEVGR GTSTYDGLSL
730 740 750 760 770 780
AWACVVDLTK RVKCLCLFAT HYFELTELGS EPGIDNYHVT AQELNGNLIL LHKVQQGPAS
790 800 810 820 830 840
QSHGLQVAKL AGIPANVIKE AQKRLRILEK QQQQHLQTSV QSDLFATLDS EVTPSTQVIE
850 860 870 880
KVIEVEVSSP ALDLLKQIEV DNLTPRQALE QLYELKAALN S