B2GDT2

PR
Gene name
xpt
Protein name
Xanthine phosphoribosyltransferase
Names
XPRTase
Species
Limosilactobacillus fermentum (strain NBRC 3956 / LMG 18251) (Lactobacillus fermentum)
KEGG Pathway
lfe:LAF_1478
EC number
2.4.2.22: Pentosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

64-137 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B2GDT2

Entry ID Method Resolution Chain Position Source
AF-B2GDT2-F1 Predicted AlphaFoldDB

No variants for B2GDT2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B2GDT2

No associated diseases with B2GDT2

1 regional properties for B2GDT2

Type Name Position InterPro Accession
domain Phosphoribosyltransferase domain 38 - 177 IPR000836

Functions

Description
EC Number 2.4.2.22 Pentosyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
xanthine phosphoribosyltransferase activity Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate.

3 GO annotations of biological process

Name Definition
purine ribonucleoside salvage Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
xanthine metabolic process The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
XMP salvage Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKELEEKIRQ FGTVLPGNVL KVDAFLNHQV DPVLMQHIGQ EFAARFKDAK ITKVWTVESS
70 80 90 100 110 120
GIAPAVMTGL ALGVPVIFAR KHKSLTLNSG MYTADVYSYT KKTTNRISIS KRYVDKTDRV
130 140 150 160 170 180
LLIDDFLANG QAVEGMLQIA DQAGVEVVGA GIVIEKCFQP GSAELAAKGV RVESLAKVSS
190
LADGQVSFKQ TEGED