B1ZZL9

PR
Gene name
lig (Oter_3148)
Protein name
Probable DNA ligase
Names
Polydeoxyribonucleotide synthase [ATP]
Species
Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1)
KEGG Pathway
ote:Oter_3148
EC number
6.5.1.1: Forming phosphoric ester bonds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

476-545 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1ZZL9

Entry ID Method Resolution Chain Position Source
AF-B1ZZL9-F1 Predicted AlphaFoldDB

No variants for B1ZZL9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1ZZL9

No associated diseases with B1ZZL9

6 regional properties for B1ZZL9

Type Name Position InterPro Accession
domain Zn-dependent metallo-hydrolase, RNA specificity domain 271 - 313 IPR011108
domain DNA ligase, ATP-dependent, N-terminal 365 - 566 IPR012308
domain DNA ligase, ATP-dependent, C-terminal 888 - 981 IPR012309
domain DNA ligase, ATP-dependent, central 663 - 901 IPR012310
conserved_site DNA ligase, ATP-dependent, conserved site 667 - 675 IPR016059-1
conserved_site DNA ligase, ATP-dependent, conserved site 844 - 868 IPR016059-2

Functions

Description
EC Number 6.5.1.1 Forming phosphoric ester bonds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA ligase (ATP) activity Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).
metal ion binding Binding to a metal ion.

6 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
DNA biosynthetic process The biosynthetic process resulting in the formation of DNA.
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
DNA repair The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPWDVKFSHG LYLPQLGWWL DAHFPQKRSF VSHAHSDHTA THDEILCSAG TAALMRARLD
70 80 90 100 110 120
AKRIEHVLPF GQTEQLTADC GVTLHPAGHI FGSAQCLLEH GEHGSLLYTG DFKLRRGRSA
130 140 150 160 170 180
EPCATPHAEL VIMETTFGRP HYVFPPTAQV LNDIATFCHE TIADDGVPVL FGYSLGKSQE
190 200 210 220 230 240
LLCSLEESQL PVMLHPQTHK LTRVYEQFGI AFPPYREFDL ATVRGHVVIC PPQSRESAFV
250 260 270 280 290 300
RRIPGHRTAM ITGWAMDPGA IYRYQCDAAF PLSDHADYQD LLRFVEAVNP QRVLTLHGFA
310 320 330 340 350 360
TEFAQTLRER GLEAWAIGED NQLELGIRSS PPQVRAGDAT PSSRSSGDAG VAAPACATPL
370 380 390 400 410 420
HAPDSFARFV AAADAVKATP KKLEKIAVLR DYLAALTPPD MGTAATFLTG RAFPQRDPRN
430 440 450 460 470 480
LTLGWSVIKR AVLEVAGVTE ADYRDAYHRF ADTGDAAGAV LAQRSLRPGD ATPSSRPEIL
490 500 510 520 530 540
GVAGVADPGP AASRPAATSA PTTCSLADMA LFFERAAAAR GPAAKLDLLR ERLALITPDE
550 560 570 580 590 600
ARYLIKIITG DLRIGLKEGL VEEALAAAAG QPLEAVREAA MLCGDIAAVA RAARTDTLAE
610 620 630 640 650 660
IQLTVFNPLQ FMLASPEPTA EAIVDRFAAQ RTAEAAAIVA GVGDPGPGSS SPATADAAPA
670 680 690 700 710 720
LARIWLEEKY DGIRCQLHKS GGRVELYSRD LNVITEQFPD LARAALALPH DFIGDGELLA
730 740 750 760 770 780
WRDGRALPFA ELQKRLGRKG GDDFFLGAEI PVSISFYDLL WLDGRSLLKE PLRERRALLE
790 800 810 820 830 840
RLLHGDATPS SRPDGDEGVA APALQPATLN PQLSTKFSLA PVTFAHTASD IEAAFLAARQ
850 860 870 880 890 900
RGNEGLMAKD PASGYTPGRR GLAWLKLKKA YATLDVVVVG VEYGHGKRRD VLSDYTFAIR
910 920 930 940 950 960
DEEHDNQLLT VGKAYSGLTD VEIAQLTQHF LEHTLEVHGR YRVVVPDTVI EVAFDTIQPS
970 980 990 1000 1010
SRHQSGFALR FPRIARIRTD KTPAEIDTLA TCRKLAAAAG SGGIAAVGAR PPPAASD