B1ZTR5

PR
Gene name
folE2
Protein name
GTP cyclohydrolase FolE2
Names
Species
Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1)
KEGG Pathway
ote:Oter_1567
EC number
3.5.4.16: In cyclic amidines
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1ZTR5

Entry ID Method Resolution Chain Position Source
AF-B1ZTR5-F1 Predicted AlphaFoldDB

No variants for B1ZTR5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1ZTR5

No associated diseases with B1ZTR5

2 regional properties for B1ZTR5

Type Name Position InterPro Accession
conserved_site GTP cyclohydrolase I, conserved site 91 - 107 IPR018234
domain GTP cyclohydrolase I domain 34 - 211 IPR020602

Functions

Description
EC Number 3.5.4.16 In cyclic amidines
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
GTP cyclohydrolase I activity Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.

1 GO annotations of biological process

Name Definition
7,8-dihydroneopterin 3'-triphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKKKSMYL HESASGAAPK IQRRYDPAFE VDAAYRASLP DMMEAAYAAI QGAHVPIQQV
70 80 90 100 110 120
GVSNFKLPLK FRTKKGEILT LEASITGTVS LEADLKGINM SRIVRSFYDH KDEVFTGEWM
130 140 150 160 170 180
GKILCAYLRN VKSKDARLKV SFSYPMLHRS LRSGLEGYQF YNVAFEGVLT RKGDYRRFIH
190 200 210 220 230 240
FDFVYSSACP CSAELAEHAR DQRGVYSVPH SQRSKARIVV EETQGKKIWI EDVHAHCLRA
250 260 270 280 290 300
LQTETQVMVK REDEQAFAEL NGAHLKFVED AARLLYREFD ADEKIADFRI ACSHLESLHS
310 320
HDAVSVICKG VKGGFTADFM DFQSLVC