B1YMC6

PR
Gene name
Exig_1033
Protein name
8-amino-7-oxononanoate synthase
Names
AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase
Species
Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 / 255-15)
KEGG Pathway
esi:Exig_1033
EC number
2.3.1.47: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1YMC6

Entry ID Method Resolution Chain Position Source
AF-B1YMC6-F1 Predicted AlphaFoldDB

No variants for B1YMC6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1YMC6

No associated diseases with B1YMC6

2 regional properties for B1YMC6

Type Name Position InterPro Accession
binding_site Aminotransferase, class-II, pyridoxal-phosphate binding site 235 - 244 IPR001917
domain Aminotransferase, class I/classII 39 - 380 IPR004839

Functions

Description
EC Number 2.3.1.47 Transferring groups other than amino-acyl groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
8-amino-7-oxononanoate synthase activity Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA.
glycine C-acetyltransferase activity Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+).
pyridoxal phosphate binding Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.

1 GO annotations of biological process

Name Definition
biotin biosynthetic process The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGFEHLRTEL EEMKQAGTFR ELVALESAQH NRVTVDGKEL IQLSSNNYLG LAAHPRLAKR
70 80 90 100 110 120
AADAALEFGA GTGSVRTIAG TLEMHQAFER ELATFKHTEA ALVFQSGFAT NLGVLSALLG
130 140 150 160 170 180
PEDVVISDAL NHASIIDGIR LTKAKRRIYN HVDLADLEAA LQETQDARTR LVVTDGVFSM
190 200 210 220 230 240
DGNIAPLPEI VELAEKYDAL VMVDDAHASG VLGKSGRGTV NHFGLDGRVA LQVGTLSKAI
250 260 270 280 290 300
GVLGGYVACE QHVKDYLIHK GRPFLFSTSH PPAVVEANRE ALRVMEEETE LFDRLWENTE
310 320 330 340 350 360
FFKHGLRELG FNIGTSTTPI TPVIVGDEAL CHQLSDRLRQ HGVFAQGIAF PTVAKGKARV
370 380
RTIVTAEHTR EDLEQALEAF KQVGQELELI