B1WY30
Gene name |
guaA |
Protein name |
GMP synthase [glutamine-hydrolyzing] |
Names |
GMP synthetase, Glutamine amidotransferase |
Species |
Crocosphaera subtropica (strain ATCC 51142 / BH68) (Cyanothece sp. (strain ATCC 51142)) |
KEGG Pathway |
cyt:cce_3266 |
EC number |
6.3.5.2: Carbon--nitrogen ligases with glutamine as amido-N-donor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B1WY30
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B1WY30-F1 | Predicted | AlphaFoldDB |
No variants for B1WY30
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B1WY30 | |||||
No associated diseases with B1WY30
4 regional properties for B1WY30
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DNA-directed DNA polymerase, family A, palm domain | 617 - 985 | IPR001098 |
| conserved_site | DNA-directed DNA polymerase, family A, conserved site | 792 - 811 | IPR019760 |
| domain | DNA mitochondrial polymerase, exonuclease domain | 113 - 392 | IPR041336 |
| domain | DNA polymerase gamma, palm domain | 631 - 1009 | IPR047580 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.5.2 | Carbon--nitrogen ligases with glutamine as amido-N-donor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| GMP synthase (glutamine-hydrolyzing) activity | Catalysis of the reaction: ATP + XMP + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate + 2H(+). |
| pyrophosphatase activity | Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glutamine metabolic process | The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTQTPSLPN | KPETLPTNTL | DKSLDRQMIV | ILDFGSQYSE | LIARRIRETQ | VYSEVLSYRT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TAQKLRQLNP | KGIILSGGPN | SVYDDRAPQC | DPDIWQLGIP | VLGVCYGMQL | MVKQLGGQVE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KALRGEYGKA | SLRIDDPTDL | LTNVEDGSTM | WMSHGDSCTR | LPEGFSILAH | TENTLCAAIA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DHDKKLFGVQ | FHPEVVHSVD | GIALIRNFVY | HICECEPTWT | TEAFVDETIR | EIRAKVRDKR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VLLALSGGVD | SSTLAFLLHQ | AIGDNLTCMF | IDQGFMRKGE | PERLMDIFDK | QFHIPVEYVN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ARDRFLKQLE | GVTDPEKKRR | LIGHEFIQVF | EEESKRLGPF | DYLAQGTLYP | DVIESADTNI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DPKTGERVAV | KIKSHHNVGG | LPKDLRFKLV | EPLRKLFKDE | VRKVGRSIGL | PEEIVRRHPF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| PGPGLAIRII | GEVTSERLNI | LRDADFVVRD | EIGKQGMYHD | FWQAFAVLLP | IRSVGVMGDQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RTYAHPIVLR | LISSEDGMTA | DWSRVPYDLL | ETISNRIVNE | VKGVNRVVYD | ITSKPPGTIE |
| WE |