B1NF18
Gene name |
CYP719B1 |
Protein name |
Salutaridine synthase |
Names |
Cytochrome P450 719B1 |
Species |
Papaver somniferum (Opium poppy) |
KEGG Pathway |
ag:ABR14720 |
EC number |
1.14.19.67: With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B1NF18
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B1NF18-F1 | Predicted | AlphaFoldDB |
No variants for B1NF18
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B1NF18 | |||||
No associated diseases with B1NF18
No regional properties for B1NF18
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B1NF18 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.19.67 | With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| iron ion binding | Binding to an iron (Fe) ion. |
| monooxygenase activity | Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water. |
| salutaridine synthase activity | Catalysis of the reaction: (R)-reticuline |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| morphine biosynthetic process | +The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPINIEGND | FWMIACTVII | VFALVKFMFS | KISFYQSANT | TEWPAGPKTL | PIIGNLHQLG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GGVPLQVALA | NLAKVYGGAF | TIWIGSWVPM | IVISDIDNAR | EVLVNKSADY | SARDVPDILK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IITANGKNIA | DCDSGPFWHN | LKKGLQSCIN | PSNVMSLSRL | QEKDMQNLIK | SMQERASQHN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GIIKPLDHAK | EASMRLLSRV | IFGHDFSNED | LVIGVKDALD | EMVRISGLAS | LADAFKIAKY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LPSQRKNIRD | MYATRDRVYN | LIQPHIVPNL | PANSFLYFLT | SQDYSDEIIY | SMVLEIFGLG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VDSTAATAVW | ALSFLVGEQE | IQEKLYREIN | NRTGGQRPVK | VVDLKELPYL | QAVMKETLRM |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KPIAPLAVPH | VAAKDTTFKG | RRIVKGTKVM | VNLYAIHHDP | NVFPAPYKFM | PERFLKDVNS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DGRFGDINTM | ESSLIPFGAG | MRICGGVELA | KQMVAFALAS | MVNEFKWDCV | SEGKLPDLSE |
| 490 | 500 | ||||
| AISFILYMKN | PLEAKITPRT | KPFRQ |