Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for B1MZH4

Entry ID Method Resolution Chain Position Source
AF-B1MZH4-F1 Predicted AlphaFoldDB

No variants for B1MZH4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1MZH4

No associated diseases with B1MZH4

5 regional properties for B1MZH4

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 341 - 510 IPR000795
domain Small GTP-binding protein domain 344 - 500 IPR005225
domain Translation initiation factor IF-2, N-terminal 265 - 313 IPR006847
domain Translation initiation factor IF- 2, domain 3 622 - 731 IPR023115
domain Translation initiation factor IF-2, domain II 516 - 611 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEEKKFSSS NRPARKQAVP ERKELPASQR RHAAKLTDGT NSSAGTTPRS NKPARQGQSQ
70 80 90 100 110 120
GQGQNRHTNS SRSNTQGGNA SRPNQSKSQG QGGRNNQRPG SRTQASEGRP MIREKKNWST
130 140 150 160 170 180
KPREGQIDYS KKTDNSLKQY VSENEKRKQA AAAKTTKKPA EQSKKAAEKP AQTKPKTAET
190 200 210 220 230 240
KTTATTTQSG TGKFGGALAS GNNSARNNSR KRNTNGTGQQ TPRRNDKPRG SKKSRRIAAK
250 260 270 280 290 300
KGPAVPATER KEQPLPAVLE YRIGMNVQDL SKLLHRDTAE IIKKLFLLGI VTNQNQSLDA
310 320 330 340 350 360
DTIEILAADY GIESQLKEEE DVADIDKFFE DDTIDESKLV ARPPVVTIMG HVDHGKTTLL
370 380 390 400 410 420
DYLRNSNVTE GEAGGITQHI GAYQTQLNGK TITFLDTPGH AAFTEMRARG ANVTDLTILV
430 440 450 460 470 480
VAADDGVMPQ TIEAINHAKA AETPIIVAVN KIDKPGANPD EVMNQLMAYD LVPEEYGGDT
490 500 510 520 530 540
IFVKISAKFG QNVDELLEMI LLQAEVLELK ANPDVPARGS VIEARLDKGR GPVATVLVQQ
550 560 570 580 590 600
GTMRVGDPIV VGNTYGRVRT MTNERGIELA EALPATPVQI TGINEVPQAG DRFIVMADEK
610 620 630 640 650 660
TARAAGEERA KRAQEAIRNS GSVVTLDTLF STMSEKAMKT VPVIVKADVQ GSVEALSGSL
670 680 690 700 710 720
KKIEVDGVRV DIIHTAVGAI NESDVTLASA SGAIIIGFNV RSTPLAKSQA DSDKVDIRFY
730 740 750 760 770 780
NVIYNAIDDV EAAMKGQLEP VFEEKVIGNV TVKELFKFSK VGIIAGAMVE EGKITKDSKV
790 800 810 820 830
RIMRDNVVVY DGEVASLQRG KDSVNEVKMG YEFGFTVAKY NDIRVGDTVE AYIMEEVKVK