B1L400
Gene name |
cas1 |
Protein name |
CRISPR-associated endonuclease Cas1 |
Names |
|
Species |
Korarchaeum cryptofilum (strain OPF8) |
KEGG Pathway |
kcr:Kcr_0423 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B1L400
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B1L400-F1 | Predicted | AlphaFoldDB |
No variants for B1L400
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B1L400 | |||||
No associated diseases with B1L400
No regional properties for B1L400
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B1L400 | |||
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| endonuclease activity | Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response to virus | Reactions triggered in response to the presence of a virus that act to protect the cell or organism. |
| maintenance of CRISPR repeat elements | Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| METTQYGHLL | IDGFGVSLRK | RRGRILILSK | GEKKEIPMKS | VKEVVIIGKA | ALSSELLKAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AQSGTDLLIA | TPTGRPVARL | IPAKAGGTAR | NRYEQYKSLE | DRRGIEIARA | VIVGKIRNQA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SNLSYYSKAR | RMDEELSSEL | YDAAQQLKRE | MEELKNEEFP | DIDEARKRIM | ARESKCANIY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WEKIASIMEE | WKFRGREKRT | DLEGNVIDPV | NLCLNVCYNL | LSAQIWKNVL | RFGLDPFLGY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LHVERPGRIS | LVYDLMEPFR | PMVDRFVFSY | LRGMSPSLFS | SNIVSGTIAS | LRSRFFSDFM |
| 310 | 320 | 330 | 340 | ||
| NWRLDYKGRK | LGMETIMFLY | VRDIVSFLRG | GKEPTMPYIP | W |