B1KHV0

PR
Gene name
mutL
Protein name
DNA mismatch repair protein MutL
Names
Species
Shewanella woodyi (strain ATCC 51908 / MS32)
KEGG Pathway
swd:Swoo_4172
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

303-468 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1KHV0

Entry ID Method Resolution Chain Position Source
AF-B1KHV0-F1 Predicted AlphaFoldDB

No variants for B1KHV0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1KHV0

No associated diseases with B1KHV0

3 regional properties for B1KHV0

Type Name Position InterPro Accession
conserved_site Translation initiation factor 3, conserved site 66 - 79 IPR019813
domain Translation initiation factor 3, N-terminal 15 - 84 IPR019814
domain Translation initiation factor 3, C-terminal 91 - 180 IPR019815

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
mismatch repair complex Any complex formed of proteins that act in mismatch repair.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTIQILSPQL ANQIAAGEVV ERPASVIKEL VENSLDAGAT RVDIEIDKGG SKLIKIQDNG
70 80 90 100 110 120
SGIPKSELNL ALSRHATSKL STLDDLDAIL SFGFRGEALA SISSVSRLTL TSRTAEQTEA
130 140 150 160 170 180
WQAYAEGSDM AVKVIPAAHP VGTTIEAVDL FFNTPARRRF LKSDKTEFTH IDEWLKRIAL
190 200 210 220 230 240
VKPEIHFTLK HNGKQVRNYR PANNQDQYLM RLAQICGKNF AEQAIEIDCQ HEGLTLSGYI
250 260 270 280 290 300
QSPFFTSPAS DTQFFYVNGR LIRDRLVNHA VRQAFSEHGT GELASYVLML EIAPHQVDVN
310 320 330 340 350 360
VHPAKHEVRF HQSRYVHDYI LQALQSALMQ VARASISLPE EKLVEFVEDD WHSKPLSTGR
370 380 390 400 410 420
VSEADPSNYA TQSKFDEKPR ESGSQGQSSS ISAPSSYSRG GEYSARSQPE LPSASEIASY
430 440 450 460 470 480
TQLLKTPQTA QASKLVNSDL KTPMPPVLAG QYWVYAGDEL SLLPIDIVAK WLVKRDILAK
490 500 510 520 530 540
IDNGLVSQPL LMPVSIKVDE DWLNTIDERE QLLRQLGIEI TIRLGQLIIK KVPPYLRQSQ
550 560 570 580 590 600
LVTVIPELLQ WVRFEEPTHE ALALWLAKQD DGKFESAVAT WSAFSQLDDE IQQELAQKAK
610
VLPWQSWLEE QLSD