B1JUG2

PR
Gene name
dapE
Protein name
Succinyl-diaminopimelate desuccinylase
Names
SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase
Species
Burkholderia cenocepacia (strain MC0-3)
KEGG Pathway
bcm:Bcenmc03_2051
EC number
3.5.1.18: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

51-127 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1JUG2

Entry ID Method Resolution Chain Position Source
AF-B1JUG2-F1 Predicted AlphaFoldDB

No variants for B1JUG2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1JUG2

No associated diseases with B1JUG2

2 regional properties for B1JUG2

Type Name Position InterPro Accession
conserved_site ArgE/DapE/ACY1/CPG2/YscS, conserved site 65 - 74 IPR001261
domain Peptidase M20, dimerisation domain 179 - 286 IPR011650

Functions

Description
EC Number 3.5.1.18 In linear amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
cobalt ion binding Binding to a cobalt ion (Co).
succinyl-diaminopimelate desuccinylase activity Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
diaminopimelate biosynthetic process The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
lysine biosynthetic process via diaminopimelate The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSATLALTEQ LIARASVTPD DQHCQQIMTE RLAALGFECE TIASHGVTNL WAVKRGTDGR
70 80 90 100 110 120
DGKLLAFAGH TDVVPTGPLE QWTSPPFIPA HRDGKLYGRG AADMKTSLAA FVVASEEFVA
130 140 150 160 170 180
VHPDHRGTIA FLITSDEEGP ATDGTVKVVE LLQARGERLD YCIVGEPTST AELGDVVKNG
190 200 210 220 230 240
RRGSMSGELV VKGVQGHIAY PHLAKNPIHL LAPALAELAA EQWDAGNEYF PPTTWQVSNL
250 260 270 280 290 300
HAGTGATNVT PGHADLLFNF RFSTASTVEG LQARVHAILD KHGLEYTLKW SVSGLPFLTP
310 320 330 340 350 360
RGELSGALEH AIRTETGITT ELSTTGGTSD GRFIARICPQ VIEFGPPNGS IHKIDEHIEV
370
RFVDPLKNVY RRVLEQLIA