B1JE34

PR
Gene name
trpC
Protein name
Indole-3-glycerol phosphate synthase
Names
IGPS
Species
Pseudomonas putida (strain W619)
KEGG Pathway
ppw:PputW619_4781
EC number
4.1.1.48: Carboxy-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-96 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1JE34

Entry ID Method Resolution Chain Position Source
AF-B1JE34-F1 Predicted AlphaFoldDB

No variants for B1JE34

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1JE34

No associated diseases with B1JE34

2 regional properties for B1JE34

Type Name Position InterPro Accession
conserved_site Indole-3-glycerol phosphate synthase, conserved site 58 - 76 IPR001468
domain Indole-3-glycerol phosphate synthase domain 5 - 265 IPR013798

Functions

Description
EC Number 4.1.1.48 Carboxy-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
indole-3-glycerol-phosphate synthase activity Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O.

1 GO annotations of biological process

Name Definition
tryptophan biosynthetic process The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVPTVLERI VARKFQEVAE RSARVSLAEM EHLAKGADAP RGFANALIEQ AKRKQPAVIA
70 80 90 100 110 120
EIKKASPSKG VIRENFVPSE IAVSYEKGGA TCLSVLTDVD YFQGADEYLQ QARAAVSLPV
130 140 150 160 170 180
IRKDFMVDPY QIIEARALGA DCVLLIVSAL DDVKMAELAA TAKEVGLDVL VEVHDGDELE
190 200 210 220 230 240
RALKTLDTPL VGVNNRNLHT FEVSLETTLD LLPRIPRDRL AITESGILNR ADVELMEIND
250 260 270
VYSFLVGEAF MRAEQPGLEL QRLFFPEQVK KTVQQLD