B1JDF0
Gene name |
purT |
Protein name |
Formate-dependent phosphoribosylglycinamide formyltransferase |
Names |
5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2 |
Species |
Pseudomonas putida (strain W619) |
KEGG Pathway |
ppw:PputW619_4162 |
EC number |
6.3.1.21: Acid--ammonia (or amine) ligases (amide synthases) |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B1JDF0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B1JDF0-F1 | Predicted | AlphaFoldDB |
No variants for B1JDF0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B1JDF0 | |||||
No associated diseases with B1JDF0
1 regional properties for B1JDF0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Amino acid permease/ SLC12A domain | 27 - 408 | IPR004841 |
Functions
| Description | ||
|---|---|---|
| EC Number | 6.3.1.21 | Acid--ammonia (or amine) ligases (amide synthases) |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ligase activity | Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| phosphoribosylglycinamide formyltransferase 2 activity | Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate. |
| phosphoribosylglycinamide formyltransferase activity | Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| 'de novo' IMP biosynthetic process | The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTRIGTPLSP | TATRVLLCGC | GELGKEVVIE | LQRLGVEVIA | VDRYANAPAM | QVAHRSHVVN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MLDGVALRAV | IEAEKPHYIV | PEIEAIATAT | LVELENEGFN | VVPTARATQL | TMNREGIRRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AAEELDLPTS | PYHFADTFED | YAKAVADVGY | PCVVKPVMSS | SGKGQSLLRS | DADLQKSWDY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AQEGGRAGKG | RVIIEGFIDF | DYEITLLTVR | HVGGTTYLEP | VGHRQEKGDY | QESWQPQAMS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PKALAESQRV | AKAVTDALGG | RGLFGVELFV | KGDQVWFSEV | SPRPHDTGLV | TLISQDLSQF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ALHARAILGL | PIPVVRQFGP | SASAVILPEG | QSQQTSFANL | GAALSEPDTA | IRLFGKPEIN |
| 370 | 380 | 390 | |||
| GQRRMGVCLA | RDESIEAARA | KATRAAQAVK | VEF |