B1IPB4
Gene name |
kefB |
Protein name |
Glutathione-regulated potassium-efflux system protein KefB |
Names |
K(+)/H(+) antiporter |
Species |
Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks) |
KEGG Pathway |
ecl:EcolC_0362 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B1IPB4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B1IPB4-F1 | Predicted | AlphaFoldDB |
No variants for B1IPB4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B1IPB4 | |||||
No associated diseases with B1IPB4
1 regional properties for B1IPB4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DAHP synthetase I/KDSA | 10 - 275 | IPR006218 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| glutathione-regulated potassium exporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state. |
| solute:proton antiporter activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out). |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEGSDFLLAG | VLFLFAAVAA | VPLASRLGIG | AVLGYLLAGI | AIGPWGLGFI | SDVDEILHFS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ELGVVFLMFI | IGLELNPSKL | WQLRRSIFGV | GAAQVLLSAA | LLAGLLMLTD | FAWQAAVVGG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IGLAMSSTAM | ALQLMREKGM | NRSESGQLGF | SVLLFQDLAV | IPALALVPLL | AGSADEHFDW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MKIGIKVLAF | VGMLIGGRYL | LRPVFRFIAA | SGVREVFTAA | TLLLVLGSAL | FMDALGLSMA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LGTFIAGVLL | AESEYRHELE | TAIDPFKGLL | LGLFFISVGM | SLNLGVLYTH | LLWVVISVVV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LVAVKILVLY | LLARLYGVRS | SERMQFAGVL | SQGGEFAFVL | FSTASSQRLF | QGDQMALLLV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TVTLSMMTTP | LLMKLVDKWL | SRQFNGPEEE | DEKPWVNDDK | PQVIVVGFGR | FGQVIGRLLM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ANKMRITVLE | RDISAVNLMR | KYGYKVYYGD | ATQVDLLRSA | GAEAAESIVI | TCNEPEDTMK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LVEICQQHFP | HLHILARARG | RVEAHELLQA | GVTQFSRETF | SSALELGRKT | LVTLGMHPHQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| AQRAQLHFRR | LDMRMLRELI | PMHADTVQIS | RAREARRELE | EIFQREMQQE | RRQLDGWDEF |
| E |