B1IA80

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Streptococcus pneumoniae (strain Hungary19A-6)
KEGG Pathway
spv:SPH_0653
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

27-363 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1IA80

Entry ID Method Resolution Chain Position Source
AF-B1IA80-F1 Predicted AlphaFoldDB

No variants for B1IA80

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1IA80

No associated diseases with B1IA80

6 regional properties for B1IA80

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 432 - 599 IPR000795
domain Small GTP-binding protein domain 434 - 591 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 51 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 352 - 403 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 707 - 822 IPR023115
domain Translation initiation factor IF-2, domain II 607 - 702 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKRLYEIA KELGKESKEV VARAKELGLD VKSHSSSVEE AVAAKIAASF KPAAAPKVEA
70 80 90 100 110 120
KPAAPKVSAE KKTEKSEPAK PAVAKEEAKP AEPVAPKTEK VAAKPQSRNF KAEREARAKE
130 140 150 160 170 180
QAERRKQNKG NNRDQQQNGN RQKNDGRNGG KQGQSNRDNR RFNDQAKKQQ GQQKRRNERR
190 200 210 220 230 240
QQEDKRSNQA APRIDFKARA AALKAEQNAE YARSSEERFK QYQAAKEALA QANKRKEPEE
250 260 270 280 290 300
IFEEAAKLAE QAQQVQAVVE VVPEKKEPAV DTRRKKQARP DKNRDDYDHE EDGPRKQQKN
310 320 330 340 350 360
RSSQNQVRNQ KNSNWNNNKK NKKGNNKNNR NQTPKPVTER KFHELPTEFE YTDGMTVAEI
370 380 390 400 410 420
AKRIKREPAE IVKKLFMMGV MATQNQSLDG ETIELLMVDY GIEAKQKVEV DNADIERFFV
430 440 450 460 470 480
EDGYLNEDEL VERPPVVTIM GHVDHGKTTL LDTLRNSRVA TGEAGGITQH IGAYQIVENG
490 500 510 520 530 540
KKITFLDTPG HAAFTSMRAR GASVTDITIL VVAADDGVMP QTIEAINHSK AVNVPIIVAI
550 560 570 580 590 600
NKIDKPGANP ERVIGELAEH GVMSTAWGGD SEFVEISAKF NQNIEELLET VLLVAEIQEL
610 620 630 640 650 660
KADPTVRAIG TVIEARLDKG KGAVATLLVQ QGTLNVQDPI VVGNTFGRVR AMTNDLGRRV
670 680 690 700 710 720
KVAGPSTPVS ITGLNEAPMA GDHFAVYEDE KSARAAGEER AKRALMKQRQ ATQRVSLENL
730 740 750 760 770 780
FDTLKAGELK SVNVIIKADV QGSVEALSAS LQKIDVEGVK VTIVHSAVGA INESDVTLAE
790 800 810 820 830 840
ASNAFIVGFN VRPTPQARQQ AEADDVEIRL HSIIYKVIEE MEEAMKGMLD PEFEEKVIGE
850 860 870 880 890 900
AVIRETFKVS KVGTIGGFMV INGKVARDSK VRVIRDGVVI YDGELASLKH YKDDVKEVTN
910 920
GREGGLMIDG YNDIKMDDVI EAYVMEEIKR