Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for B1HR05

Entry ID Method Resolution Chain Position Source
AF-B1HR05-F1 Predicted AlphaFoldDB

No variants for B1HR05

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1HR05

No associated diseases with B1HR05

7 regional properties for B1HR05

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 389 - 558 IPR000795
domain Small GTP-binding protein domain 393 - 548 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 52 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 314 - 364 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 56 - 94 IPR013575
domain Translation initiation factor IF- 2, domain 3 665 - 779 IPR023115
domain Translation initiation factor IF-2, domain II 565 - 658 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTKIRVHEYA KQVNKTSKEV IEALSKLNVS VTNHMSMLEK DIVSKLNQTF KATPEKNVGK
70 80 90 100 110 120
QATQNISQKS QSNGQQNHSV KKQEGQRQQS ATSKPKVNNQ QHSNSSNEKS KNTKGNQNRN
130 140 150 160 170 180
MTQNNNNNNN NNNNNRRGGG GYNQRPKPGI HGGKRRHPKT HQPSIPVKQK ELPEKITFVE
190 200 210 220 230 240
SLSVAELAKK LHREPSEIIK KLFMLGVMAT INQELDKDAI ELICADYGVE VEEEIRVDIT
250 260 270 280 290 300
DLETHFEQTE EVNEAQLSER PPVVTIMGHV DHGKTTLLDS IRNTKVTAGE AGGITQHIGA
310 320 330 340 350 360
YQVTEGDKKI TFLDTPGHAA FTTMRARGAK VTDLTILVVA ADDGVMPQTV EAINHAKAAE
370 380 390 400 410 420
VPIIVAVNKM DKPSANPDRV MQELTEHGLV PEAWGGETIF VPISALKGEG IDTLLEMILL
430 440 450 460 470 480
VAEVGELKAN PDRLALGTVI EAQLDKGRGS VATLLVQDGT LKVGDPIVVG HTFGRVRAMV
490 500 510 520 530 540
NDKGRRVKEA GPSTPVEITG LNDVPQAGDR FVVFEDEKTA RQVGETRAMS AIQAQRSEKQ
550 560 570 580 590 600
RVTLDNLFEQ MSQGEMKELN LIVKADVQGT VEAMAASLMK IDVEGVNVKI IHTGAGAITE
610 620 630 640 650 660
SDISLAAASN AIVIGFNVRP DVNAKRAAEE EGVDIRLHRI IYKVIEEIEQ AMKGMLDPEF
670 680 690 700 710 720
EEKIIGQAEV RQTIKVSKVG TIAGSYVTEG KVTRDSGVRV IRDNVVIFEG ELDTLKRFKD
730 740 750
EVKEVARGYE CGITITNFND IKEGDIIEAY IMEEVKRV