B1H0C7
Gene name |
mutL |
Protein name |
DNA mismatch repair protein MutL |
Names |
|
Species |
Endomicrobium trichonymphae |
KEGG Pathway |
rsd:TGRD_476 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B1H0C7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B1H0C7-F1 | Predicted | AlphaFoldDB |
No variants for B1H0C7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B1H0C7 | |||||
No associated diseases with B1H0C7
4 regional properties for B1H0C7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aminotransferase class V domain | 29 - 187 | IPR000192-1 |
| domain | Aminotransferase class V domain | 213 - 471 | IPR000192-2 |
| domain | Molybdenum cofactor sulfurase, C-terminal | 635 - 780 | IPR005302 |
| domain | Molybdenum cofactor sulfurase, middle domain | 513 - 631 | IPR005303 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mismatch repair complex | Any complex formed of proteins that act in mismatch repair. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| ATP-dependent DNA damage sensor activity | A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis. |
| mismatched DNA binding | Binding to a double-stranded DNA region containing one or more mismatches. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mismatch repair | A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPINILSQET | VNKIAAGEVV | ERPLNAVKEL | VENSLDAFAS | SITVEIEEAG | KKLIRVSDNG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FGMDKKDLEL | SILRHATSKI | DDFKDLMHIH | SLGFRGEALA | SIAAVSNFAI | KTRKKGENSG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| WKLSVAGAKD | IKVMPWSGAE | GTITEVKSLF | FNTPARQKFL | KSDSTERSRI | INSLEETALA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NYDISFKIFS | ENKTVFSAAQ | TDSKTERIAD | ILGKDFAKTL | KNIKIDHPKI | SLDVYFTGRD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NSLPNKKYQY | LFVNSRPVNY | PKRLMHCVYQ | SYKESIPRDK | YPGILIYTDV | DPSEIDVNIH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PAKREVKFAD | ENGIYDILFK | ALRNALMSQG | HPEIKITYPP | LDKEKSAKQE | VEGSTAPRFP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KIQQPVIYAR | EPKPKYNYAS | LKQTCSIDKY | ADVFAKQEEL | TPENFDSNIK | VIGQVFDTYI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IASNKGDLYI | FDQHAAAERV | RYEFYLSQMK | SQTIKIQQML | MPENFDLSPS | ISELLKANIN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| IFNELGISIE | EFGQNSFRIT | AYPALLGNIS | MEQIVKTIIS | DIEDDKHAEI | EQKRDKIIRS |
| 550 | 560 | 570 | 580 | 590 | |
| ACRASIKAGD | NVSFIEAKKL | INDLFKCKQP | FTCPHGRPTA | YKISLNEIEK | FFKRK |