B1AZA5

PR
Gene name
Tmem245
Protein name
Transmembrane protein 245
Names
Species
Mus musculus (Mouse)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B1AZA5

Entry ID Method Resolution Chain Position Source
AF-B1AZA5-F1 Predicted AlphaFoldDB

39 variants for B1AZA5

Variant ID(s) Position Change Description Diseaes Association Provenance
rs239809164 7 P>S No EVA
rs27838036 211 R>Q No EVA
rs3394339007 223 I>K No EVA
rs3388686903 235 W>* No EVA
rs3388680758 239 V>E No EVA
rs3388674162 249 V>M No EVA
rs3388683318 269 Q>K No EVA
rs219060732 301 T>A No EVA
rs27854308 305 D>E No EVA
rs229867191 316 S>A No EVA
rs3388690243 393 V>SDG* No EVA
rs3394278517 402 H>N No EVA
rs27854315 402 H>R No EVA
rs3388674163 415 R>Q No EVA
rs1135255448 438 L>F No EVA
rs3394296566 452 K>N No EVA
rs3394320939 454 L>I No EVA
rs3388689646 482 H>Y No EVA
rs3388664322 493 S>N No EVA
rs3388690202 502 N>K No EVA
rs3388684397 514 Q>R No EVA
rs3394016565 524 A>P No EVA
rs3388674733 539 L>I No EVA
rs3388674178 568 W>* No EVA
rs3388683417 604 S>P No EVA
rs3388678717 655 S>T No EVA
rs3388683326 673 Y>N No EVA
rs3388684364 675 K>T No EVA
rs3388683293 677 V>M No EVA
rs3388686886 683 L>P No EVA
rs3388678819 715 A>D No EVA
rs3388664305 730 G>D No EVA
rs3388683269 733 I>N No EVA
rs3388686872 782 L>S No EVA
rs3388688010 791 I>M No EVA
rs3388680383 818 E>V No EVA
rs3388686254 828 C>S No EVA
rs3388677302 830 L>F No EVA
rs3394249948 861 Q>H No EVA

No associated diseases with B1AZA5

No regional properties for B1AZA5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for B1AZA5

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADRGGPAEA PSPRGSPRPE SRAPRTVGPG ETPRTAALAL RFDKPIKQAF YNTGAVLFVC
70 80 90 100 110 120
LCCGAAVLVY FILEAFLRPL LWAVLCGTFL HPFKSSLTRL GRLWLRRLHR AHTPIVLAAL
130 140 150 160 170 180
LLPLCFADYG VEALGEQALR RRRLLLLLGA GGPLLYGLYC LGSYLGVQVL LAHAGALICR
190 200 210 220 230 240
GLDYFSSLWI WTLVVGYVLM VSFKWNASTQ RYLRAVSIPV WMILLFHIAS LAGSWRIPVF
250 260 270 280 290 300
LVIVFLMSVG TLYEKQNEKE SAGAELPGQV ISMAASTLAN LAISITGYES STEDQPSDPP
310 320 330 340 350 360
TEPTDKGEPP PALSASSSSS SRSSPSSPSP TLGRQRPEMG TFLRKKKTSD IYFVSLVWAI
370 380 390 400 410 420
IAVQLWLNLW IVQLLPVPVA VWIIKKLVIH FGVVGFLEKR CHAWWQVIEC FLKERQEALA
430 440 450 460 470 480
PWPIIGLGKF LLKVDSKLWH WLNKKMIIWL EKMLDKIISI FIIFLLVIGT LLLALLLTAK
490 500 510 520 530 540
VHQESVHMIE VTSSLINETL ANHPEWANWL PEAQVVQRAL NSAANNVYQY GREWITHKLH
550 560 570 580 590 600
KILGDKVNNT AVIEKQVLEL WDRLYHSWFV KNVTHSGRHK GHKMHVSRQN SWLGDILDWQ
610 620 630 640 650 660
DIASFVHENI ETFLSILESL WIVMSRNVSL LFTTVTTLLT ILFYSGTALL NFVLSLIIFL
670 680 690 700 710 720
TTLFYLLSSS DEYYKPVKWV ISLTPLSQPG PSSNIIGQSV EEAIRGVFDA SLKMAGFYGL
730 740 750 760 770 780
YTWLTHTIFG INIVFIPSAL AAILGAVPFL GTYWAAVPAV LDLWLTQGLG CKAILLLVFH
790 800 810 820 830 840
LLPTYFVDTA IYSDISGGGH PYLTGLAVAG GAYYLGLEGA IIGPILLCIL VVASNIYSAM
850 860 870
LVSPTNSMPT PNQTPWPAQT QRTFRDISED LKSSVD