Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for B1AIV8

Entry ID Method Resolution Chain Position Source
AF-B1AIV8-F1 Predicted AlphaFoldDB

No variants for B1AIV8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B1AIV8

No associated diseases with B1AIV8

5 regional properties for B1AIV8

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 115 - 283 IPR000795
domain Small GTP-binding protein domain 120 - 270 IPR005225
domain Translation initiation factor IF-2, N-terminal 38 - 86 IPR006847
domain Translation initiation factor IF- 2, domain 3 392 - 501 IPR023115
domain Translation initiation factor IF-2, domain II 290 - 385 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKKNIKQKK DNRIAIDVKK HIKKVDVGVF DGTFVFTSPL SISELAPKLN KSPNEIIMRY
70 80 90 100 110 120
FKKGVVYNLN TILDEEQIGE LCLEYDLDFK IEKNVNTENL LENIYFDDLE IDLVARAPIV
130 140 150 160 170 180
TIMGHVDHGK TTLLDTIRKS SITASEAGGI TQHIGAYQII KDNRAITFID TPGHEAFTEM
190 200 210 220 230 240
RARGANLTDI VILVVAADDG IKMQTEEAID HAKAANVPII VFVNKMDKYE ANPEKVLNQL
250 260 270 280 290 300
SAKEIVAEEL GGDVVFVKGS ALKNEGISEL LDSILLIAEL NNYKANPNRL AYGTTIEANL
310 320 330 340 350 360
DKGHGPLATL LVQNGTLRKG DYLVVGSTYG KIRNMFDEYD NEIEIALPSK PVKVSGFEEV
370 380 390 400 410 420
PTAGDKFLAL ADEKQARAIA NDVKQKKMRL ERAMLQSSDI RTKIANGELK NINLIIKADV
430 440 450 460 470 480
QGSLEALKGI FSSINIEGVT TTLIRSAIGT ISESDVRLAQ TSDAIIIGFN VRASRIIKDL
490 500 510 520 530 540
ADSVGVQIMN YDIIYKFKED LELWMKGTLD PIIIEEVIGE AKVLKLFKHS QVGTICGCRV
550 560 570 580 590 600
INGKIKRNAL VRVLRDGIVI YNSKIATLQH NKDSVNEVIA DKECGLTIAN FNDIKENDII
610
EVYIKVEKKH DEVK