B0Y581
Gene name |
AFUB_071700 |
Protein name |
Mannitol 2-dehydrogenase |
Names |
M2DH, MDH |
Species |
Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus) |
KEGG Pathway |
|
EC number |
1.1.1.67: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B0Y581
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B0Y581-F1 | Predicted | AlphaFoldDB |
No variants for B0Y581
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B0Y581 | |||||
No associated diseases with B0Y581
No regional properties for B0Y581
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B0Y581 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.67 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mannitol 2-dehydrogenase activity | Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAPLKLNSRN | LSQIAAAGGA | LVKIPTYQRG | RAVKEGIVHI | GVGGFHRAHL | AVYIDQLMQK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HGVNDYAICG | VGLQPFDSAM | RDALASQDHL | YTLIERSAKG | SFAHVIGSIN | SYLFAPDNRE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AVIAKMAHPD | TKIVSLTITE | SGYYYNENTH | ELQSEHPDIQ | FDLDPANEKA | PRTTFGFLYA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GLTRRYQQGL | KPFTVMSCDN | MQKNGSITRH | MLESFARLRN | PEVAEWIAEE | GAFPNAMVDR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ITPQTSETDK | TALAEKFGIV | DSWPVVTEPF | TQWVIEDQFS | DGRPPFEKVG | VQVVKDVHAV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EQFEKHKLRL | LNGSHSALGY | PGQLAGFQYV | HEVMANPLFR | KFVWQMMQEE | VKPLLPEIPG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VDIDEYCNTL | IERFTNPTIM | DQLPRICLNA | SGKIPQFIMP | SIAEAIWETG | PFRRLCFVAA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AWFHYIKGVD | DRGKPFEVVD | PMREELQAKA | RAGGNDPSEL | LSIKSLFGDD | LRNDERFLRE |
| 490 | 500 | ||||
| ITTAMNDIAR | DGIMKTLPKY | IN |