B0Y1E7

PR
Gene name
ncs2 (ctu2, AFUB_060070)
Protein name
Cytoplasmic tRNA 2-thiolation protein 2
Names
Species
Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) (Aspergillus fumigatus)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

121-198 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0Y1E7

Entry ID Method Resolution Chain Position Source
AF-B0Y1E7-F1 Predicted AlphaFoldDB

No variants for B0Y1E7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0Y1E7

No associated diseases with B0Y1E7

4 regional properties for B0Y1E7

Type Name Position InterPro Accession
domain GNAT domain 519 - 758 IPR000182
domain Helicase domain 279 - 479 IPR007807
domain tRNA(Met) cytidine acetyltransferase TmcA, N-terminal 9 - 202 IPR013562
domain Possible tRNA binding domain 770 - 1004 IPR027992

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
nucleotidyltransferase activity Catalysis of the transfer of a nucleotidyl group to a reactant.
tRNA binding Binding to a transfer RNA.

3 GO annotations of biological process

Name Definition
protein urmylation Covalent attachment of the ubiquitin-like protein URM1 to another protein.
tRNA thio-modification The addition a sulfur atom to a nucleotide in a tRNA molecule.
tRNA wobble uridine modification The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQVCWFERFG GGNQLLTVLS SSRTCYARFV NFKVFKRMEN YRLRRNMPRT GPCKLLLPLS
70 80 90 100 110 120
CGISSSVLLH ILNAQIQHEL AKSHPSPGFD LHLLVIEPSS ISHSSLSYDE GFELLQQTFP
130 140 150 160 170 180
LHSFTRIPLH SIFELDPELQ EVISQFSKDG FVDDTGLSAK ERLDAFRASI PTSTSKVDVD
190 200 210 220 230 240
YILITRLVVA FAKKIACRGV LWGDTDTRLA AKTLANVAKG RGSSLTWQVC DGMSPFGVEF
250 260 270 280 290 300
NFPLRDLFKA EVDNYASFFP ELTRIIIPDE PPSENVLTKN LSIDELMMRY VQTQGEKYPG
310 320 330 340 350 360
VMANVTRTAS KLQASLMPAN VPQCSFCGAF MLNSGNNDGG DTTGASRALE LCYACIRSRP
ELTC