B0TP70
Gene name |
lpxB |
Protein name |
Lipid-A-disaccharide synthase |
Names |
|
Species |
Shewanella halifaxensis (strain HAW-EB4) |
KEGG Pathway |
shl:Shal_2968 |
EC number |
2.4.1.182: Hexosyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B0TP70
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B0TP70-F1 | Predicted | AlphaFoldDB |
No variants for B0TP70
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B0TP70 | |||||
No associated diseases with B0TP70
No regional properties for B0TP70
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for B0TP70 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.4.1.182 | Hexosyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipid-A-disaccharide synthase activity | Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSNNPHVFA | MVAGEISGDI | LGAGLIKALK | TRYPDAKFVG | IGGPRMEALG | FESIFSYEEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AVMGIVEVLS | RLPRLLKVRA | TLIDELVKIN | PDCFIGIDAP | DFNIGLELKL | KNRGIKTVHY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VSPSVWAWRP | KRIFKIAKAT | DMVLSLLPFE | KAFYDKHQVP | CTFVGHTLAD | DIELESDKAQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ARELLGLDKE | AEYLAILPGS | RGGELKMLAE | PFVKAASLIK | QRYPDIKFVT | PLVNQKRRDQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FEQALREHAP | DLEIDLVEGQ | SREVMAAADC | ILLASGTATL | EAMLVKRPMV | VAYRVSPITY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RIAKGMMLTK | RYSLPNLLAD | DDVVEELIQA | DCTPEKIATA | VATQLDNDFS | PMYDRFMQMH |
| 370 | 380 | ||||
| KSLRCDASAR | AADAVIKLVE | DKV |