B0TIX7

PR
Gene name
rlmL
Protein name
Ribosomal RNA large subunit methyltransferase K/L
Names
Species
Shewanella halifaxensis (strain HAW-EB4)
KEGG Pathway
shl:Shal_2353
EC number
2.1.1.173: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

131-202 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0TIX7

Entry ID Method Resolution Chain Position Source
AF-B0TIX7-F1 Predicted AlphaFoldDB

No variants for B0TIX7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0TIX7

No associated diseases with B0TIX7

3 regional properties for B0TIX7

Type Name Position InterPro Accession
domain Ribosomal RNA large subunit methyltransferase K/L-like, FLD domain 162 - 371 IPR000241
domain THUMP domain 31 - 154 IPR004114
domain S-adenosylmethionine-dependent methyltransferase 484 - 666 IPR019614

Functions

Description
EC Number 2.1.1.173 Methyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
23S rRNA (guanine(2445)-N(2))-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.
RNA binding Binding to an RNA molecule or a portion thereof.
rRNA (guanine-N7-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLNFFAAAPR GYEYALSLEL AELGASEIKE SVAGVYFSAP LELGYRITLW SRLASRIIFV
70 80 90 100 110 120
IYKGPCESPE QLYNAAYGID WQMQFSNRST FSIDFHGLGG FIKNTQFGAL KIKDAIVDRF
130 140 150 160 170 180
RDDDFSRPNV ERVDADFRID AHFRRGEITI GFNFSGPALH KRGYRSTTGE APLKENLAAN
190 200 210 220 230 240
MLVRSGWQAA QVDLLDPFCG SGTILIEAAM MACDIAPGIH RERFGFDHWL PHNKKVWEEL
250 260 270 280 290 300
LNEARARASI GKTRCEIKFY GSDIDSRLVA LAKRNAENAG VLELIDFNVC NALDVKAPAG
310 320 330 340 350 360
SGYLISNPPY GERLGNVTSL LQLYYQLGDK FKADFGGWSI AILNSDVELL SALKLKADKQ
370 380 390 400 410 420
MKMNNGALEC AFNLYTVHAL NTRRVDPANI KIEGDVSDIA VPFANRIKKN FKQLEKWAKK
430 440 450 460 470 480
EGIDSYRLYD ADIPEYNVAI DKYLDYVVIQ EYSAPSEIPE AVTKRRLTDV LISLPSAIGI
490 500 510 520 530 540
DPNHIILKTR ERKKGTNQYE KLAASKLELI TTEYGAKFKL NLKEYLDTGL FLDHRLTRKL
550 560 570 580 590 600
VGEKSKGRSV CNLFSYTGSA SVHAALGGAT SVTTVDMSNT YIDWAKENFA LNGLNSDKYQ
610 620 630 640 650 660
FVQANCLQWM KRTHDRFDLI FIDPPTFSNS KRMEDSFDVQ RDHLAMLTDV FKLLNPGGEI
670 680 690 700 710
IFSNNKRKFK MEIAELEALG MSVKNIDNQT LPLDYKRNPH IHNTWLITHA G