B0SEW5

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Leptospira biflexa serovar Patoc (strain Patoc 1 / Ames)
KEGG Pathway
lbf:LBF_2759
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

830-918 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0SEW5

Entry ID Method Resolution Chain Position Source
AF-B0SEW5-F1 Predicted AlphaFoldDB

No variants for B0SEW5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0SEW5

No associated diseases with B0SEW5

7 regional properties for B0SEW5

Type Name Position InterPro Accession
domain SecA DEAD-like, N-terminal 6 - 384 IPR011115
domain SecA Wing/Scaffold 646 - 855 IPR011116
domain SecA, preprotein cross-linking domain 228 - 340 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 89 - 247 IPR014001
domain SecA motor DEAD 3 - 647 IPR014018
conserved_site SecA conserved site 482 - 497 IPR020937
domain SecA, C-terminal helicase domain 402 - 617 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFQKILTILF GSKYERDLKR LNPIVETINS FEVTIKAMDD ETLSSQTKKF KERLASGETL
70 80 90 100 110 120
DDILPEAFAT VREVAYRTLG MRHFDVQMMG GISLHWGNIS EMKTGEGKTL TSTLPIYLNS
130 140 150 160 170 180
LSGEGVHVVT VNDYLAKRDA NWMRPVFEFL KVSVGVIQHD MDHEERKVAY NSDITYGTNN
190 200 210 220 230 240
EFGFDYLRDN MVSYKEHRVQ RQHNFAIVDE VDSILIDEAR TPLIISGPAE ESTDKYLKVN
250 260 270 280 290 300
KIIPKLVEGE DFEIDEKAKN VILSEAGVHH VEKLLEVDNL YHAENIELVH HVQQALKAHK
310 320 330 340 350 360
IFFKDKDYVV QDGEVIIVDE FTGRLMKGRR YSDGLHQSLE AKEGVPIARE SQTLASITFQ
370 380 390 400 410 420
NYFRIYKKLA GMTGTADTEA EEFKKIYNLD VIVIPSNLKI QRQDMPDRVY KTEREKFDAV
430 440 450 460 470 480
VKDIQEKVSR KQPVLVGTIS IEKSEVLSKL LFSHGIQHNV LNAKQHERES EIVANAGKPG
490 500 510 520 530 540
AITIATNMAG RGTDIVLGGA PKYKDDLEKL DDKCDSLGIK NKEELEIIYS FRECLIKQKF
550 560 570 580 590 600
DEAEGKISDV RNETIKKECI KILGDAKKWK VDHDFVIGAG GLHIIGSERH ESRRIDNQLR
610 620 630 640 650 660
GRSGRQGDPG SSRFYLSLQD DLMRIFGSDR IARIMDTLKM PEGQELEHSM VSNAIARAQK
670 680 690 700 710 720
RVEGHNFDIR KHLLEYDDVM NRQRIYIYGI RNELLDKGNM SKTVFDFFDE VVENQVILYC
730 740 750 760 770 780
EGNNADAWEI DSLNEWLQSL GIDHKIESKD FKKESNPQLK VFEVVSKLVK ELYDYKVSSI
790 800 810 820 830 840
GDEIWRSIER NVFLDILDHR WKEHLYAMDH LKEGIWTVGY GEKNPLIEYK LQGFKMFDQL
850 860 870 880 890 900
VDNLKNEVVS FLLKIEVTES DKKQDDTSPK EYKKIGQEQR AEVDMFGNEL KSNKTKPQVS
910
STTSSGGGSE RRSSRRKK