B0S4Q5

PR
Gene name
map6
Protein name
Microtubule-associated protein 6 homolog
Names
MAP-6 homolog, Stable tubule-only polypeptide homolog, STOP
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

268-378 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0S4Q5

Entry ID Method Resolution Chain Position Source
AF-B0S4Q5-F1 Predicted AlphaFoldDB

No variants for B0S4Q5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0S4Q5

No associated diseases with B0S4Q5

2 regional properties for B0S4Q5

Type Name Position InterPro Accession
domain Zinc finger, RING-type 53 - 100 IPR001841
domain Zinc finger, RING-CH-type 45 - 106 IPR011016

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
microtubule Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.

2 GO annotations of molecular function

Name Definition
calmodulin binding Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
microtubule binding Binding to a microtubule, a filament composed of tubulin monomers.

3 GO annotations of biological process

Name Definition
dendrite morphogenesis The process in which the anatomical structures of a dendrite are generated and organized.
lysosome localization Any process in which a lysosome is transported to, and/or maintained in, a specific location.
microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O73737 MAP6 Microtubule-associated protein 6 homolog Gallus gallus (Chicken) PR
10 20 30 40 50 60
MAWPCVTRAC CIARFGNLQD KGDIAVPLMY SKYSEVTDGA QPPPPRPGSA AIETQPSLSD
70 80 90 100 110 120
PYSGSLGRFS KKPESARGSV MRQDYQAWKA NPEPSCKPRI EYQPSEAPLE RETQYKKDFR
130 140 150 160 170 180
SWPIPRQGDH PWIPKLSPSP TMPVIASDDK RKKDFVAPKA PPAEIKLINA EQPESAKGRG
190 200 210 220 230 240
PTAFIAAPEI LISVVQETNE IQKRESFMPK LPAKEPRATR DTGSPHPAQA RGERGAGTSY
250 260 270 280 290 300
RNEFRPWTDV KPVKPIKAKS QYQPPEEKVV HETSYKATFK GESNQPAAGD NKLMERRRIR
310 320 330 340 350 360
SLYSEPSKES SKVEKPSVQT SKPKKTSTSH KPVKKAKEKI MASGRASKKK GAESSSTTKP
370
EEKEKSKEIN NKLAEAKE