B0S198

PR
Gene name
pyrB
Protein name
Aspartate carbamoyltransferase
Names
Aspartate transcarbamylase, ATCase
Species
Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508) (Peptostreptococcus magnus)
KEGG Pathway
fma:FMG_0720
EC number
2.1.3.2: Carboxy- and carbamoyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

41-117 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0S198

Entry ID Method Resolution Chain Position Source
AF-B0S198-F1 Predicted AlphaFoldDB

No variants for B0S198

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0S198

No associated diseases with B0S198

2 regional properties for B0S198

Type Name Position InterPro Accession
domain Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 152 - 300 IPR006131
domain Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 5 - 143 IPR006132

Functions

Description
EC Number 2.1.3.2 Carboxy- and carbamoyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
amino acid binding Binding to an amino acid, organic acids containing one or more amino substituents.
aspartate carbamoyltransferase activity Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate.

3 GO annotations of biological process

Name Definition
'de novo' pyrimidine nucleobase biosynthetic process The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
'de novo' UMP biosynthetic process The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKNRNLINA DDFNVEEINE ILNLAEEIIK SPSDFSNLCN GKILGTLFFE PSTRTRLSFE
70 80 90 100 110 120
SAIHRLGGDC IGFSESASSS TSKGESLADT IRTVSNYTDI IAMRNPKEGS AVLASSYAEV
130 140 150 160 170 180
PLINAGDGGH QHPTQTLTDL LTIWMTKKKL DNMTIGLCGD LKFGRTVHSL IKAMSRYENN
190 200 210 220 230 240
KFILISPEEL QVPDYIKMFL KSKNIEFKEV EKMEDVIGEL DVLYMTRVQK ERFFNEADYV
250 260 270 280 290 300
RLKDSYILDN DKMKLATEDL AVLHPLPRVN EIATEVDSDP RAVYFKQVRY GVIVRMALIL
KLLGVR