B0RHD6

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / DSM 20744 / JCM 9667 / LMG 2889 / C-1) (Corynebacterium sepedonicum)
KEGG Pathway
cms:CMS1237
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-47 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0RHD6

Entry ID Method Resolution Chain Position Source
AF-B0RHD6-F1 Predicted AlphaFoldDB

No variants for B0RHD6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0RHD6

No associated diseases with B0RHD6

3 regional properties for B0RHD6

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 290 - 299 IPR020557
domain Fumarate lyase, N-terminal 33 - 315 IPR022761
domain Argininosuccinate lyase, C-terminal 378 - 446 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTESTDPSSR AGEAGALWGG RFAGGPSPEL VALSRSTHFD WQLAPYDIAG SRAHARALAA
70 80 90 100 110 120
AGYLSDAERQ AMLQALDTLE DRVRSGALVA SEADEDVHGA LERGLMDIAG PDLGGKLRAG
130 140 150 160 170 180
RSRNDQIATL VRMYLRDHAA VIHAMLVQLV DALAAQAEAA GGAIMPGRTH LQHAQPVLLA
190 200 210 220 230 240
HHLLAHCWPL VRDLERLADW DARADVSPYG SGALAGSTLG LDASAVARDL GFARSSENSI
250 260 270 280 290 300
DGTAARDVVA EFAFVLAQVG IDLSRLSEEI ILWNTREFGF VTLSDSFSTG SSIMPQKKNP
310 320 330 340 350 360
DIAELARGKS GRLIGNLSGL LATLKGLPLA YNRDLQEDKE PVFDSVQTLE VLLPAFTGMI
370 380 390 400 410 420
ATLRFDVDRM AELAPQGFSL ATDVAEWLVK HRVAFRDAHE ITGELVKLAE SRGVGLEDLS
430 440 450 460 470 480
DDDLRAVSPH LVPEVREVLS IDGSVASRDG VGGTARVRVD EQRAELVRRV AELRARADAA
490
AERRAAASAA ASA