B0JNB0
Gene name |
ispE |
Protein name |
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase |
Names |
CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase |
Species |
Microcystis aeruginosa (strain NIES-843 / IAM M-2473) |
KEGG Pathway |
mar:MAE_04520 |
EC number |
2.7.1.148: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B0JNB0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B0JNB0-F1 | Predicted | AlphaFoldDB |
No variants for B0JNB0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B0JNB0 | |||||
No associated diseases with B0JNB0
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.148 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity | Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+). |
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway | The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
| terpenoid biosynthetic process | The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MHSYTLLAPA | KINLYLEIVG | DRPDGFHELV | MVMQTVALCD | RITLRPNGLQ | EFRLFCHHPL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VPQDSSNLAH | RAATLMAKEF | PRLFANYGGI | DITIEKYIPV | AAGLAGGSTN | AAAVLVGIDL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IWELGLTRPE | LETLAARLGS | DTSFCVTGGT | VICTGRGEIL | DPIAPLTGLW | VILAKYDHLS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VSTPWAYQSY | RQKFQDTYLS | SPEDFHHRRQ | QVSSGALVQA | IAQKKPAAIG | KFIHNDLEKV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VLPEFPLVAE | LRQVLGDLGG | LGTMMSGSGP | TVFTLCSSQE | VAETIVKEAR | EILVAPDLQF |
| 310 | |||||
| WIAPITDTGI | QVT |