B0G107
Gene name |
DDB_G0272484 |
Protein name |
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 homolog |
Names |
dNTPase |
Species |
Dictyostelium discoideum (Slime mold) |
KEGG Pathway |
ddi:DDB_G0272484 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B0G107
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B0G107-F1 | Predicted | AlphaFoldDB |
No variants for B0G107
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B0G107 | |||||
No associated diseases with B0G107
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| deoxynucleoside triphosphate hydrolase activity | Catalysis of the reaction: dNTP + H2O = 2'-deoxynucleoside + H+ + triphosphate. |
| dGTPase activity | Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate. |
| GTP binding | Binding to GTP, guanosine triphosphate. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response to virus | Reactions triggered in response to the presence of a virus that act to protect the cell or organism. |
| dGTP catabolic process | The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNNTFKYVNE | DVSGTEGEES | DYDPSEFIRG | YHESPRSPRL | IDYEMGRGLM | GNFKGLGINK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VRQSNEYDND | TDYSSRKSSK | IINDVIHGHM | EVPDYIMDFI | DTEQFQRLRD | LKQVGTTSFV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FPCASHSRFE | HSIGVSHLAG | KYIDRIKVTQ | PELEITEREQ | KFVRIAGLCH | DLGHGPFSHA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FESWVDQLGG | SKRFHHEDMS | IKMLNWIIDD | HGLDEYDSDD | IKFISSLIQG | KHRPKERAFI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YDIVANNRNS | VDVDKFDYLS | RDSYYLGRST | VCDFQRLMEF | SKVIDDQICF | LSKEIYNLYE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LFHTRYSLHK | LVYTHKVGKS | IEFMIADAFT | EADQFLKISD | QLEDPKEFIN | LSDSLLRRIE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TSKEPELEKS | RKIIKNIRNR | NLYKFVDEII | VSTDKIRWSA | DSLAEDIAKV | GNGILESDII |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VQNLKLNYAF | KDKDPVQSTR | FYTRYDSTQS | FTIKKEETSH | LIPNQFQEER | IRIFCRSKEK |
| 490 | 500 | 510 | |||
| CEQVQTAFRK | LLKNHNLSPN | PSFTVSPARN | IKKI |