B0CQL3

PR
Gene name
MMM1
Protein name
Maintenance of mitochondrial morphology protein 1
Names
Species
Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor)
KEGG Pathway
lbc:LACBIDRAFT_300811
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

19-100 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0CQL3

Entry ID Method Resolution Chain Position Source
AF-B0CQL3-F1 Predicted AlphaFoldDB

No variants for B0CQL3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0CQL3

No associated diseases with B0CQL3

4 regional properties for B0CQL3

Type Name Position InterPro Accession
domain MMM1 domain 12 - 46 IPR019411-1
domain MMM1 domain 72 - 204 IPR019411-2
domain MMM1 domain 214 - 262 IPR019411-3
domain Synaptotagmin-like mitochondrial-lipid-binding domain 73 - 277 IPR031468

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Single-pass type I membrane protein
  • The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions
  • These foci are often found next to mtDNA nucleoids
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ERMES complex A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles.
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
lipid binding Binding to a lipid.

3 GO annotations of biological process

Name Definition
lipid transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
mitochondrial genome maintenance The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
protein insertion into mitochondrial outer membrane The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPNNYVFSLQ PTFTQGLILG QLSILVLLGM ILKFLFLDST QHPFESSSVD TDLLRRKRGL
70 80 90 100 110 120
EPRHLPEELL HDNAESAEWF NVLLRQIVDV YRSKLRDGLP GIEGDEIARR RIENYANKIR
130 140 150 160 170 180
PSGFLDHIEI HSVDLGVSAP ELFNARVRQN APSPAETEFD ATYTDTLSLS LSTSYLFNYP
190 200 210 220 230 240
MQSFARLPIS LTISLSQFKS SICIIPPEIT SPTPVLTISI SPNFVLDLST TSLMGSRAKL
250 260 270 280 290
ANVPKLHELI QHQVRRILAA RATWKVVLPG LASVVDVKEE IKKEMSDADL S