B0CF30

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Acaryochloris marina (strain MBIC 11017)
KEGG Pathway
amr:AM1_5596
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

821-883 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0CF30

Entry ID Method Resolution Chain Position Source
AF-B0CF30-F1 Predicted AlphaFoldDB

No variants for B0CF30

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0CF30

No associated diseases with B0CF30

5 regional properties for B0CF30

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 657 - 847 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 34 - 145 IPR007695
domain DNA mismatch repair protein MutS, core 309 - 632 IPR007696
domain DNA mismatch repair protein MutS, connector domain 154 - 290 IPR007860
domain DNA mismatch repair protein MutS, clamp 470 - 560 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSDSVAPDVP VIREGKNPAQ HRDRTTVDRE ALSPMMRHYV DLKDEYPQTI LLYRMGDFYE
70 80 90 100 110 120
TFFEDACTIA QALELVLTSR QSGNEVGRVA MAGIPHHQLD RYSRLLVEKG FAVAICDQME
130 140 150 160 170 180
DPAQAQGLVK REVTRVITPG TLLEEGMLNA RSNNFLAAFV LAGNHWGLAY ADISTGEFLT
190 200 210 220 230 240
TQFSERETLA QELLRLQPSE VLFPTDAPDI QQILRPGEQS DLLPEGLPNQ FCYSLRSQTS
250 260 270 280 290 300
FTQAEARQRI QEVYGVRSLE GLGCEHLPLA VRAAGGLLAY LEATQKDTHI PLQPLATYTL
310 320 330 340 350 360
SQYLVLDHQS RRNLELTQTS RDGTFRGSLL WAIDRTRTAM GSRALRRWLL QPLLDLNDIQ
370 380 390 400 410 420
ARQAAITELL PQTGFRKELQ NQLQKIYDLE RLAGRAGSGT ANARDLVALA ESLGQLTELS
430 440 450 460 470 480
HKVAKCEAQY LQALQTVPPI LDQLAQRLRA HLVESPPISL TEGGLIKPSV NPELDQMRQQ
490 500 510 520 530 540
IVSDQQWIAN LEKDERERTG ISTLKVGFNK AFGYFISISR AKADQAPDDY IRKQTLTNEE
550 560 570 580 590 600
RFITPELKER EARIFTAQTE QFQLEYDLFV TLRTEVGEQA SLIRTVAAAV SAVDILVGLT
610 620 630 640 650 660
EVAVYQGYCC PTMSDSREIQ ILDGRHPVVE QSLPPGFFVP NATELGSAPS AELTPHPDLV
670 680 690 700 710 720
ILTGPNASGK SCYLRQVGLI QLMAQIGSYV PAQSARLGIC DRIFTRVGAV DDLATGQSTF
730 740 750 760 770 780
MVEMNETANI LNHASSKSLV LLDEIGRGTA TFDGLAIAWS VAEHLAAVIQ ARTIFATHYH
790 800 810 820 830 840
ELNELASLVE NVANYQVLVK ELPDQIIFLH QVCPGGASRS YGIEAGRLAG LPPSVIKRAK
850 860 870 880
QVMKQIEQHS KIAVGLRKGN TQPRARKSSA ETEAKTQQFE LPF