B0BTA9
Gene name |
nfo |
Protein name |
Probable endonuclease 4 |
Names |
Endodeoxyribonuclease IV, Endonuclease IV |
Species |
Actinobacillus pleuropneumoniae serotype 3 (strain JL03) |
KEGG Pathway |
apj:APJL_0375 |
EC number |
3.1.21.2: Endodeoxyribonucleases producing 5'-phosphomonoesters |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for B0BTA9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-B0BTA9-F1 | Predicted | AlphaFoldDB |
No variants for B0BTA9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for B0BTA9 | |||||
No associated diseases with B0BTA9
6 regional properties for B0BTA9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, DNA glycosylase/AP lyase-type | 229 - 263 | IPR000214 |
| domain | Zinc finger, FPG/IleRS-type | 235 - 263 | IPR010663 |
| domain | Formamidopyrimidine-DNA glycosylase, catalytic domain | 1 - 111 | IPR012319 |
| domain | DNA glycosylase/AP lyase, H2TH DNA-binding | 126 - 221 | IPR015886 |
| binding_site | DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site | 238 - 262 | IPR015887 |
| domain | Nei, N-terminal | 2 - 116 | IPR044091 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.21.2 | Endodeoxyribonucleases producing 5'-phosphomonoesters |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| deoxyribonuclease IV (phage-T4-induced) activity | Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| zinc ion binding | Binding to a zinc ion (Zn). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKYIGAHVSA | SGGVENAVLR | AVEIGANAFA | LFTKNQRQWK | APALKADTIE | KFKRFCKAHQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FSPEHILPHD | SYLINLGNPE | AENLAKSREA | FIDEMERANQ | LGLKLLNFHP | GAHLNKISES |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ECLARIAESI | NIAVDKVPNV | IAVIENTAGQ | GSNLGYRFEH | LAEIIDQVED | KNRVGVCLDT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| CHLFSAGYDI | SSLESCEQTF | SEFERTVGFQ | YLRGMHLNGS | KTPLGSRVDR | HHTLREGTIG |
| 250 | 260 | 270 | |||
| TDFCKFIMQD | DRFDNIPLIL | ETIQPEIWTE | EIKFLRTLAK |