B0B9A0

PR
Gene name
cdu1 (CTL0247)
Protein name
Deubiquitinase and deneddylase Dub1
Names
ChlaDub1
Species
Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
KEGG Pathway
ctb:CTL0247
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

47-161 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

8 structures for B0B9A0

Entry ID Method Resolution Chain Position Source
5B5Q X-ray 170 A PDB
5HAG X-ray 210 A A 130-401 PDB
6FDK X-ray 160 A A 155-401 PDB
6FDQ X-ray 230 A A/B 155-401 PDB
6FDU X-ray 230 A A/B 155-401 PDB
6GZS X-ray 190 A A 130-401 PDB
6GZT X-ray 210 A A 130-401 PDB
AF-B0B9A0-F1 Predicted AlphaFoldDB

No variants for B0B9A0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0B9A0

No associated diseases with B0B9A0

1 regional properties for B0B9A0

Type Name Position InterPro Accession
domain Ulp1 protease family, C-terminal catalytic domain 130 - 366 IPR003653

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Host cell
  • Membrane ; Single-pass membrane protein
  • Secreted, and delivered into the host cell
  • Located predominantly on the plasma membrane and to a lesser extent on intracellular membranes, especially the host cell nuclear envelope
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
host cell A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
cysteine-type deubiquitinase activity An thiol-dependent isopeptidase activity that cleaves ubiquitin from a target protein to which it is conjugated.
deNEDDylase activity An isopeptidase activity that cleaves NEDD8 from a target protein to which it is conjugated.

2 GO annotations of biological process

Name Definition
protein deneddylation The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
protein deubiquitination The removal of one or more ubiquitin groups from a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLSPTNSTSK TAPVPPRDSS KPVLISEEPR NQLLQKVART ALAVLLVVVT LGLILLFYSF
70 80 90 100 110 120
SDLQSFPWCC QTHPSTKEQP TISIPVPLPS PPLAVPRPST PPPPVISRPS TPSAPKPSTP
130 140 150 160 170 180
PPLLPKAPKP VKTQEDLLPL VPEQVFVEMY EDMARRQTIE ALVPAWDSDI IFKCLCYFHT
190 200 210 220 230 240
LYPGLIPLET FPPATIFNFK QKIISILEDK KAVLRGEPIK GPLPICCSKE NYRRHLQRTT
250 260 270 280 290 300
LLPVFMWYHP TPKTLSDTMQ TMKQLAIKGS VGASHWLLVI VDIQARRLVY FDSLYNYVMP
310 320 330 340 350 360
PENMKKELQS FAQQLDQVYP AYDSKKFSVK IAAKEVIQRG SGSSCGAWCC QFLHWYLKDP
370 380 390 400
LTDALNDLPV DSVERHENLA SFVQACEAAV QDLPELSWPE A