B0B8A5

PR
Gene name
lpxA
Protein name
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase
Names
UDP-N-acetylglucosamine acyltransferase
Species
Chlamydia trachomatis serovar L2 (strain 434/Bu / ATCC VR-902B)
KEGG Pathway
ctb:CTL0793
EC number
2.3.1.129: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

229-280 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for B0B8A5

Entry ID Method Resolution Chain Position Source
AF-B0B8A5-F1 Predicted AlphaFoldDB

No variants for B0B8A5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for B0B8A5

No associated diseases with B0B8A5

3 regional properties for B0B8A5

Type Name Position InterPro Accession
repeat Hexapeptide repeat 104 - 137 IPR001451
conserved_site Hexapeptide transferase, conserved site 148 - 176 IPR018357
domain UDP N-acetylglucosamine O-acyltransferase, C-terminal 175 - 256 IPR029098

Functions

Description
EC Number 2.3.1.129 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity Catalysis of the reaction: (R)-3-hydroxytetradecanoyl- + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine.

1 GO annotations of biological process

Name Definition
lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNIHPTAIV EDGARIGNNV TIEPYAIVKK SVTLCDDVVV KSYAYIDGFT TIGRGTTVWP
70 80 90 100 110 120
SAMIGNKPQD LKFKGEKTFV EIGEHCEIRE FAMITSSTFE GTTVSIGNNC LIMPWAHIAH
130 140 150 160 170 180
NCSVGNNVVF STHVQLAGHV QVGDCVTIGS MVGVHQFVRI GSYSMVGAMS GIRRDIPPFT
190 200 210 220 230 240
IGTGNPYALG GINKVGLQRR QVSFETRLAL IKTFKRVFRS DESFQASLES VLEDFGEVPE
250 260 270
VRHFVEFCRQ PSKRGIERGV DCEASLEEPI DKKEGAFVES