A9WHV4

PR
Gene name
dcd
Protein name
dCTP deaminase
Names
Deoxycytidine triphosphate deaminase
Species
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
KEGG Pathway
cau:Caur_0990
EC number
3.5.4.13: In cyclic amidines
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

138-186 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9WHV4

Entry ID Method Resolution Chain Position Source
AF-A9WHV4-F1 Predicted AlphaFoldDB

No variants for A9WHV4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9WHV4

No associated diseases with A9WHV4

2 regional properties for A9WHV4

Type Name Position InterPro Accession
domain dUTPase-like 67 - 179 IPR029054
domain dUTPase, trimeric 71 - 155 IPR033704

Functions

Description
EC Number 3.5.4.13 In cyclic amidines
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
dCTP deaminase activity Catalysis of the reaction: dCTP + H2O = dUTP + NH3.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.

3 GO annotations of biological process

Name Definition
dUMP biosynthetic process The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).
dUTP biosynthetic process The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate.
nucleobase-containing small molecule interconversion The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPIKSDRWIR RMALEHGMIE PFVDHQVRRG VISYGLTSYG YDMRVTDHFK VFTNVYNALV
70 80 90 100 110 120
DPKQFDPRSF VDIRADYVDI PPNSFALAQS LEYFRIPRTV SCIVIGKSSY ARCGIIINVT
130 140 150 160 170 180
PLEPEWEGHV TIEISNTTPL PARIYAHEGI GQVLFLESDE PCEVSYADKK GKYQGQTGIV
LPRIDP