A9WH99

PR
Gene name
coaD
Protein name
Phosphopantetheine adenylyltransferase
Names
Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT
Species
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
KEGG Pathway
cau:Caur_2402
EC number
2.7.7.3: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

109-161 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9WH99

Entry ID Method Resolution Chain Position Source
AF-A9WH99-F1 Predicted AlphaFoldDB

No variants for A9WH99

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9WH99

No associated diseases with A9WH99

1 regional properties for A9WH99

Type Name Position InterPro Accession
domain Cytidyltransferase-like domain 3 - 133 IPR004821

Functions

Description
EC Number 2.7.7.3 Nucleotidyltransferases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
pantetheine-phosphate adenylyltransferase activity Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.

1 GO annotations of biological process

Name Definition
coenzyme A biosynthetic process The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRIAIYPGSF DPVTYAHLDI ARRATRIFDR VIMAVFDRPQ KRLLFSTAER LQLLQAVTAD
70 80 90 100 110 120
LVNVEATSYE MLTVEFARQV GACAIVRGLR AGSDFEAEFQ MAQVNQTIDP NIEVVVLMAG
130 140 150 160
RQFAHISSTA VREMASLGRD PVEFTPPVVV AALREKFAQR G