A9VJG1

PR
Gene name
mqo
Protein name
Probable malate:quinone oxidoreductase
Names
MQO, Malate dehydrogenase [quinone]
Species
Bacillus mycoides (strain KBAB4) (Bacillus weihenstephanensis)
KEGG Pathway
bwe:BcerKBAB4_2768
EC number
1.1.5.4: With a quinone or similar compound as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

14-87 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A9VJG1

Entry ID Method Resolution Chain Position Source
AF-A9VJG1-F1 Predicted AlphaFoldDB

No variants for A9VJG1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A9VJG1

No associated diseases with A9VJG1

3 regional properties for A9VJG1

Type Name Position InterPro Accession
domain Protein kinase domain 20 - 299 IPR000719
conserved_site Mitogen-activated protein (MAP) kinase, conserved site 55 - 153 IPR003527
active_site Serine/threonine-protein kinase, active site 137 - 149 IPR008271

Functions

Description
EC Number 1.1.5.4 With a quinone or similar compound as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
malate dehydrogenase (menaquinone) activity Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol.
malate dehydrogenase (quinone) activity Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol.

1 GO annotations of biological process

Name Definition
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNMQQKTDV ILIGAGIMSA TLGSLLKELA PEWEIKVFEK LANAGEESSN EWNNAGTGHS
70 80 90 100 110 120
ALCELNYTSE KSDGSIDIGK AVKVNEQFQL SRQFWAYLVK RNLIRNPQDF IMPLPHMSLV
130 140 150 160 170 180
QGEKNVEFLK KRFEALSKNA LFQGMEFADA PDTLKKWLPL IMEGRNSNEP MAATKIDSGT
190 200 210 220 230 240
DVNFGALTRM LFDYLKTKNV ELNYKHSVEN IKRAKNGLWE VKVHDMNSGK IEHHTAKFVF
250 260 270 280 290 300
IGGGGGSLPL LQKTGIPESK HIGGFPVSGL FMVCKNQKIV EQHHAKVYGK AKVGAPPMSV
310 320 330 340 350 360
PHLDTRYIDN KKALLFGPFA GFSPKFLKTG SNLDLIGSVK PNNVLTMLAA GVKEMGLTKY
370 380 390 400 410 420
LIQQVMLSHE KRMEELREFI PNAKSEDWDT VVAGQRVQVI KDTDAGGKGT LQFGTEVVSA
430 440 450 460 470 480
NDGSIAALLG ASPGASTAVH VMLEVLEKCF PERILEWEPK IKEMVPSYGV SLTENPRLFQ
490
ELHASTGRTL GLNEKEAVHN